This book describes the state of the art in the field of bioanalytical nano- and microsystems with optical functionality. In 12 chapters distinguished scientists and leaders in their respective fields show how various optical technologies have been miniaturized and integrated over the last few decades in order to be combined with nano- and microsystems for applications in the life sciences. The main detection and characterization technologies are introduced, and examples of the superiority of these integrated approaches compared to traditional ones are provided. Examples from e.g. the fields of optical waveguides, integrated interferometers, surface plasmon resonance or Raman spectroscopy are introduced and discussed, and it is shown how these approaches have led to novel functionalities and thereby novel applications.
Author(s): Poenar Daniel Puiu (auth.), Wolfgang Fritzsche, Jürgen Popp (eds.)
Series: Springer Series on Chemical Sensors and Biosensors 10
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2012
Language: English
Pages: 332
Tags: Analytical Chemistry;Nanotechnology and Microengineering;Medical Biochemistry;Optics, Optoelectronics, Plasmonics and Optical Devices;Nanotechnology;Biochemistry, general
Front Matter....Pages i-xii
Front Matter....Pages 1-1
Color Sensors and Their Applications....Pages 3-45
Addressing of Concentration Spaces for Bioscreenings by Micro Segmented Flow with Microphotometric and Microfluorimetric Detection....Pages 47-81
Nanotechnology for Diagnostic and Sensing: Soft and Advanced Imaging/Sensing Approaches to Analyze Biomolecules....Pages 83-99
Front Matter....Pages 101-101
Integrated Optical Microsystems for Interferometric Analytics....Pages 103-153
Refractometric Photonic Chips for Biosensing....Pages 155-180
Front Matter....Pages 181-181
Surface Plasmon Resonance Bioanalytical Platform to Appraise the Interaction Between Antimicrobial Peptides and Lipid Membranes....Pages 183-210
Biological Applications of Surface Plasmon Resonance Imaging....Pages 211-226
Front Matter....Pages 227-227
Lab-on-a-Chip Surface-Enhanced Raman Spectroscopy....Pages 229-245
Microfluidic Raman Spectroscopy for Bio-chemical Sensing and Analysis....Pages 247-268
Front Matter....Pages 269-269
Polymeric Microfluidic Devices for High Performance Optical Imaging and Detection Methods in Bioanalytics....Pages 271-288
Chip Systems for Analysis of Nucleic Acids with Integrated Amplification and Detection....Pages 289-304
Optofluidic Microsystems for Application in Biotechnology and Life Sciences....Pages 305-323
Erratum to: Chip Systems for Analysis of Nucleic Acids with Integrated Amplification and Detection....Pages 324-324
Back Matter....Pages 325-329
