Occupational Exposures: Chemical Carcinogens and Mutagens offers a focused emphasis on chemical exposures associated with carcinogenic and mutagenic impacts along with associated controls for mitigating and controlling exposures. It discusses a range of topics including hematopoietic system impact, reproductive system impact, inorganic compounds, halogenated compounds, carbamates, polycyclic aromatic hydrocarbons, aromatic amines, product elimination and substation, exposure control methods, and human biological impact.
- Presents a comprehensive account of carcinogens and mutagens for occupational and environmental health professionals
- Covers preventive measures and controls for carcinogens and mutagens
- Discusses exposure controls, exposure pathways, impacts, and treatments
The book is ideal for professionals and graduate students in the fields of occupational health and safety, industrial engineering, and chemical engineering.
Author(s): Frances Alston, Onwuka Okorie
Series: Sustainable Improvements in Environment Safety and Health
Publisher: CRC Press
Year: 2023
Language: English
Pages: 208
City: Boca Raton
Cover
Half Title
Series Page
Title Page
Copyright Page
Table of Contents
Authors
1 Polycyclic Aromatic Hydrocarbons
1.1 Introduction
1.1.1 Benzene
1.2 Exposure Pathways
1.2.1 Inhalation Exposures and Impact
1.2.2 Dermal Exposures and Impact
1.2.3 Ingestion Exposure and Impact
1.3 Chemical to Human Interface
1.4 Exposure Control Methods
1.4.1 Product Elimination and Substation
1.4.2 Engineering Controls
1.4.3 Administrative Controls
1.4.4 Protective Equipment and Effectiveness
1.5 Human Biological Impact
1.5.1 Potential Impact to Exposed Individual
1.5.2 Potential Impact to Offsprings
1.6 Treatment of Resultant Illness
References
2 Aromatic Amines
2.1 Introduction
2.2 Heterocyclic Aromatic Amines
2.3 Exposure Pathways
2.3.1 Inhalation Exposures and Impact
2.3.2 Dermal Exposures and Impact
2.3.3 Ingestion Exposure and Impact
2.4 Chemical to Human Interface
2.5 Exposure Control Methods
2.5.1 Product Elimination and Substation
2.5.2 Engineering Controls
2.5.3 Administrative Controls
2.5.4 Protective Equipment and Effectiveness
2.6 Human Biological Impact
2.6.1 Potential Impact to Offsprings
2.7 Treatment of Resultant Illness
References
3 Nitrosamines
3.1 Introduction
3.2 Exposure Pathways
3.2.1 Inhalation Exposure and Impact
3.2.2 Dermal Exposure and Impact
3.2.3 Ingestion Exposure and Impact
3.3 Chemical to Human Interface
3.4 Exposure Control Methods
3.4.1 Product Elimination and Substitution
3.5 Administrative Controls
3.6 Personal Protective Equipment
3.7 Human Biological Impact
3.7.1 Potential Impact on Exposed Individual
3.7.2 Potential Impact to Off-Spring
3.8 Treatment of Resultant Illness
References
4 Azo Dyes
4.1 Introduction
4.1.1 Azo Dye Production
4.2 Chemical to Human Interface
4.3 Exposure Pathways
4.3.1 Inhalation Exposures and Impact
4.3.2 Dermal Exposures and Impact
4.3.3 Ingestion Exposure and Impact
4.4 Exposure Control Methods
4.4.1 Product Elimination and Substitution
4.4.2 Engineering Controls
4.4.3 Administrative Controls
4.4.4 Protective Equipment and Effectiveness
4.5 Human Biological Impact
4.6 Treatment of Resultant Illness
References
5 Carbamates
5.1 Introduction
5.1.1 Carbamate Used as Therapeutics
5.2 Exposure Pathways
5.2.1 Inhalation Exposures and Impact
5.2.2 Dermal Exposures and Impact
5.3 Exposure Control Methods
5.3.1 Product Elimination and Substation
5.3.2 Engineering Controls
5.3.3 Administrative Controls
5.3.4 Protective Equipment and Effectiveness
5.4 Human Biological Impact
5.4.1 Potential Impact on Exposed Individual
5.4.2 Potential Impact on Off-Spring
5.5 Treatment of Resultant Illness
Decontamination
Respiratory
Atropine
Oxime
Benzodiazepines
Disposition
5.6 Technical Information
References
6 Halogenated Compounds
6.1 Introduction
6.2 Halogenated Hydrocarbons
6.3 Halogenated Organic Compounds
6.4 Halogenated Solvents
6.5 Exposure Pathways
6.5.1 Inhalation Exposures and Impact
6.5.2 Dermal Exposures and Impact
6.5.3 Ingestion Exposure and Impact
6.6 Chemical to Human Interface
6.7 Exposure Control Method
6.7.1 Product Elimination and Substation
6.7.2 Engineering Controls
6.7.3 Administrative Controls
6.7.4 Protective Equipment and Effectiveness
6.8 Human Biological Impact
6.8.1 Potential Impact to Exposed Individual
6.8.2 Potential Impact on Offspring
6.9 Treatment of Resultant Illness
References
7 Inorganic Compounds
7.1 Introduction
7.2 Exposure Pathways
7.2.1 Inhalation Exposures and Impact
7.2.2 Dermal Exposure Impact
7.2.3 Ingestion Exposure and Impact
7.3 Chemical to Human Interface
7.4 Exposure Control Methods
7.4.1 Product Elimination and Substation
7.4.2 Engineering Controls
7.4.3 Administrative Controls
7.4.4 Protective Equipment and Effectiveness
7.5 Human Biological Impact
7.5.1 Potential Impact on Exposed Individual
7.5.2 Potential Impact on Offspring
7.6 Treatment of Resultant Illness
References
8 Chemical Carcinogens
8.1 Introduction
8.1.1 Mechanism of Cancer Formation
8.1.2 Common Carcinogens
8.1.2.1 Asbestos
8.1.2.2 Benzene
8.1.2.3 Hexavalent Chromium
8.1.2.4 Formaldehyde
8.1.2.5 Silica
8.1.2.6 Vinyl Chloride
8.1.2.7 IARC
8.1.2.8 ACGIH
8.1.2.9 NTP
8.2 Exposure Pathways
8.2.1 Inhalation Exposures and Impact
8.2.2 Dermal Exposures and Impact
8.2.3 Ingestion Exposure and Impact
8.3 Exposure Control Methods
8.3.1 Engineering Controls
8.3.2 Administrative Controls
8.3.3 Protective Equipment and Effectiveness
8.4 Potential Impact on Exposed Individual
8.5 Potential Impact on Offspring
8.6 Treatment of Resultant Illness
References
9 Mutagens
9.1 Introduction
9.2 Classification of Mutagens
9.3 Factors Affecting Actions of Mutagens
9.4 Common Types of Mutagens
9.4.1 Base Analogues
9.4.2 Intercalating Agents
9.4.3 Metal Ions
9.4.4 Alkylating Agents
9.5 Exposure Pathways
9.5.1 Inhalation Exposures and Impact
9.5.2 Dermal Exposures and Impact
9.6 Exposure Control Methods
9.6.1 Elimination of Hazards
9.6.2 Engineering Controls
9.6.3 Administrative Controls
9.6.4 Personal Protective Equipment and Effectiveness
9.6.4.1 Dermal Protective PPE
9.6.4.2 Respiratory Protection
9.7 Treatment of Resultant Illness
References
10 Chemical Agents and Occupational-Related Diseases
10.1 Introduction
10.2 Occupational Diseases From Chemical Exposures
10.3 Prevention of Occupational-Related Diseases Resulting From Chemicals
10.3.1 Occupational Cancers
10.3.2 Occupational Skin Diseases
10.3.3 Occupational Respiratory Disease
References
Appendix A: Exposure and Risk Assessment Strategy
Appendix B: Exposure Monitoring
Appendix C: Personal Protective Equipment
Appendix D: Medical Surveillance
Index
