It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives. Every year nearly 3 million Europeans are diagnosed with cancer, leading to around 800,000 deaths per year. These deaths occur not only in aging populations, but also in children and adults who are in the most active period of their lives. This represents a tremendous problem that cannot be ignored by politicians or citizens. Fortunately, there is a constantly growing awareness that although cancer is a problem to be dealt with by clinicians, it should also be the concern of everyone. This volume contains the lectures held at the International Symposium on Cancer "New Trends in Cancer for the 21st Century". Fundamental researchers, politicians and representatives from patient coalitions share here their knowledge and interests as well as their concerns and experiences. Not only do these papers provide state-of-the-art information on cancer, they are also an opportunity to look at the problem from different points of view. It can be encouraging to realise that we are not alone in this fight.
Author(s): P. Picci, K. Scotlandi, M. Serra, A. Rizzi (auth.), Antonio Llombart-Bosch, Vicente Felipo, José Antonio López-Guerrero (eds.)
Series: Advances in Experimental Medicine and Biology 587
Edition: 2
Publisher: Springer Netherlands
Year: 2006
Language: English
Commentary: 64267
Pages: 396
City: New York, NY
Tags: Cancer Research; Oncology; Pathology; Molecular Medicine; Biotechnology
Front Matter....Pages i-xxiv
Prognostic and Therapeutic Targets in the Ewing's Family of Tumors (PROTHETS)....Pages 1-12
Targeted Therapies in Ewing's Sarcoma....Pages 13-22
The CCN3 Protein and Cancer....Pages 23-40
Ews-Fli1 in Ewing's Sarcoma: Real Targets and Collateral Damage....Pages 41-52
Molecular Karyotyping in Sarcoma Diagnostics and Research....Pages 53-63
TuBaFrost: European Virtual Tumor Tissue Banking....Pages 65-74
Virtual Microscopy in Virtual Tumor Banking....Pages 75-86
Harmonizing Cancer Control in Europe....Pages 87-93
The Diagnosis of Cancer: “From H&E to Molecular Diagnosis and Back“....Pages 95-97
From Morphological to Molecular Diagnosis of Soft Tissue Tumors....Pages 99-113
Prediction of Response to Neoadjuvant Chemotherapy in Carcinomas of the Upper Gastrointestinal Tract....Pages 115-120
Integrating the Diagnosis of Childhood Malignancies....Pages 121-137
Preclinical Models for Cell Cycle-Targeted Therapies....Pages 139-147
WWOX, a Chromosomal Fragile Site Gene and its Role in Cancer....Pages 149-159
From Genome to Proteome in Tumor Profiling: Molecular Events in Colorectal Cancer Genesis....Pages 161-177
Effect of Hypoxia on the Tumor Phenotype: The Neuroblastoma and Breast Cancer Models....Pages 179-193
Methylation Patterns and Chemosensitivity in NSCLC....Pages 195-209
Pharmacogenomics and Colorectal Cancer....Pages 211-231
Development of Pharmacogenomic Predictors for Preoperative Chemotherapy of Breast Cancer....Pages 233-249
Vascular Endothelial Growth Factor Inhibitors in Colon Cancer....Pages 251-275
Molecular Imaging of Cancer Using PET and SPECT....Pages 277-284
MRS as Endogenous Molecular Imaging for Brain and Prostate Tumors: FP6 Project “eTUMOR“....Pages 285-302
From Linac to Tomotherapy: New Possibilities for Cure?....Pages 303-308
Targeting mTOR for Cancer Treatment....Pages 309-327
AntiTumor-Associated Antigens IGGS: Dual Positive and Negative Potential Effects for Cancer Therapy....Pages 329-340
Synergistic Molecular Mechanisms in Hormone-Sensitive Breast Cancer....Pages 341-374
Back Matter....Pages 375-386
....Pages 387-396
