Karger, 2012. - 157 p.
Allergy and allergic diseases have increased in prevalence dramatically over the last decades. Relevant determinants influencing the development of allergic inflammation come from the environment and are either enhancing – promoting allergy – or protective in nature. The lack of protective factors such as early stimulation of the immune system through infection or parasite infestation by improved hygiene seems to go along with allergy promoting effects of environmental pollutants such as traffic exhaust – fine or ultrafine particles – or tobacco smoke in the indoor air. Climate change with higher CO
2 concentrations in the atmosphere and increases in the Earth’s surface temperature may contribute to an increase in allergic diseases by prolonging the flowering period of pollinating plants and immigration of allergenic neophytes. This volume brings together a carefully selected list of articles based upon lectures given at the International Symposium ‘New Trends in Allergy VII’ together with the ‘6th Georg Rajka Symposium on Atopic Dermatitis’ organized in Munich in July 2010. At this symposium, two remarkable traditions were joined: the symposia ‘New Trends in Allergy’, which began in 1980 in Munich and have since been held in 5- year intervals in Munich, Hamburg and Davos.
Contents:Preface.
Allergy in Evolution.
Climate Change, Environment and Allergy.
The Hygiene Hypothesis Does Not Apply to Atopic Eczema in Childhood.
Molecular Genetics of Atopic Eczema.
Mechanisms of Immune Tolerance to Allergens.
Th17 and Th22 in Skin Allergy.
IL- 25 Induces Both Inflammation and Skin Barrier Dysfunction in Atopic Dermatitis.
Angiogenesis, Lymphangiogenesis and Atopic Dermatitis.
What Can Dogs Bring to Atopic Dermatitis Research?
Can Microbial Superantigens Influence Atopic Dermatitis Flares?
Inflammation- Induced Alterations in the Skin Barrier Function: Implications in Atopic Dermatitis.
Itch and Eczema.
Eczema Herpeticum.
Bone Mineral Density in Patients with Atopic Dermatitis.
Immunosuppressive Effect of Prolactin- Induced Protein.
Is Food Allergy Testing Reliable in Pediatric Atopic Dermatitis? A Population- Based Study.
New Strategies for Dealing with Staphylococcus aureus Colonization and the Emerging Methicillin- Resistant Staphylococcus aureus Epidemic in Atopic Dermatitis.
Anti- IL- 4 as a New Strategy in Allergy.
New Drug Targets in Atopic Dermatitis.
Latest Approaches to Treating Atopic Dermatitis.
Author Index.
Subject Index.