Preface
Contents
Abbreviations
Contributors
Section 1: The subject matter and approach to psychiatry
1. The patient’s perspective • Kay Redfield Jamison and Adam Ian Kaplin
2. Public attitudes and the challenge of stigma • Nicole Votruba, Mirja Koschorke, and Graham Thornicroft
3. Global mental health • Crick Lund, Dörte Bemme, and Judy Bass
4. The history of psychiatry as a medical specialty • Pierre Pichot and Guy M. Goodwin
5. New ethics for twenty-first century psychiatry • Matthew L. Baum, Julian Savulescu, and Ilina Singh
6. Foundations of phenomenology/descriptive psychopathology • Hans-Jürgen Möller
7. DSM-5 and ICD-11 classifications • Darrel A. Regier, David P. Goldberg, Bedirhan T. Üstün, and Geoffrey M. Reed
8. The National Institute of Mental Health Research Domain Criteria: an alternative framework to guide psychopathology research • Charles A. Sanislow, Sarah E. Morris, Jennifer Pacheco, and Bruce N. Cuthbert
9. Application of research evidence in clinical practice • Andrea Cipriani, Stefan Leucht, and John R. Geddes
10. A neuroscience-based nomenclature for psychotropic drugs • Guy M. Goodwin, Joseph Zohar, and David J. Kupfer
Section 2: The scientific basis of psychiatric aetiology and treatment
11. Neurodevelopment • Karl Zilles and Nicola Palomero-Gallagher
12. Neuroimaging technologies • Mark Woolrich, Mark Jenkinson, and Clare Mackay
13. The connectome • Olaf Sporns
14. Neurotransmitters and signalling • Trevor Sharp
15. Psychoneuroimmunology • Juan C. Leza, Javier R. Caso, and Borja García-Bueno
16. Functional genomics • Caleb Webber
17. Cognitive neuroscience: principles and methods • Anna Christina Nobre
18. Ageing and the human brain • Verena Heise, Enikő Zsoldos, and Klaus P. Ebmeier
19. Development of brain stimulation • Andrea Crowell, Patricio Riva-Posse, and Helen S. Mayberg
20. Adherence to treatment in psychiatry • Amy Chan and Rob Horne
Section 3: Intellectual disabilities
21. Core dimensions of intellectual disabilities • Anthony J. Holland
22. Epidemiology and course of intellectual disabilities • Sally-Ann Cooper
23. Aetiology of intellectual disability and its clinical features • Judith L. Rapoport, Dale Zhou, and Kwangmi Ahn
24. Management and treatment of intellectual disability • José L. Ayuso-Mateos and Cary S. Kogan
Section 4: Autism spectrum disorders
25. Core dimensions of autism spectrum disorders • Fred R. Volkmar and Scott L. J. Jackson
26. Basic mechanisms and treatment targets for autism spectrum disorders • Emily J. H. Jones
27. Epidemiology of autism • Charles R. Newton
28. Genetics of autism spectrum disorders • Abha R. Gupta, Thomas V. Fernandez, and Ellen J. Hoffman
29. Imaging of autism spectrum disorders • Christine Ecker and Declan Murphy
30. Management and treatment of autism spectrum disorders • Emily Simonoff
Section 5: Attention-deficit/ hyperactivity disorder
31. Core dimensions of attention-deficit/hyperactivity disorder • Eric Taylor
32. Basic mechanisms and treatment planning/targets for attention-deficit/hyperactivity disorder • Barbara Franke and Jan K. Buitelaar
33. Epidemiology of attention-deficit/hyperactivity disorder and the implications for its prevention • Guilherme V. Polanczyk
34. Genetics of attention-deficit/ hyperactivity disorder • Kate Langley and Anita Thapar
35. Insights from neuroanatomical imaging into attention-deficit/hyperactivity disorder throughout the lifespan • Philip Shaw and Eszter Szekely
36. Management and treatment of attention-deficit/hyperactivity disorder • Alessandro Zuddas and Sara Carucci
Section 6: Motor disorders
37. Neurodevelopmental motor disorders • Davide Martino and Antonella Macerollo
Section 7: Delirium, dementia, and other cognitive disorders
38. Pathways of neurodegeneration underlying dementia • Noel J. Buckley and George K. Tofaris
39. Delirium • Ravi S. Bhat and Kenneth Rockwood
40. Alzheimer’s disease • Ivan Koychev and John Gallacher
41. Frontotemporal dementias • Akitoshi Takeda and Bruce Miller
42. Prion disease • Akin Nihat, TzeHow Mok, and John Collinge
43. Dementia with Lewy bodies • Anto P. Rajkumar and Dag Aarsland
44. Dementia in Parkinson’s disease • Michele Hu and Fahd Baig
45. Dementia due to Huntington’s disease • Russell L. Margolis
46. Vascular cognitive impairment • Joanne A. Byars and Ricardo E. Jorge
47. Traumatic brain injury • Christian Lepage, Inga K. Koerte, Vivian Schultz, Michael J. Coleman, and Martha E. Shenton
Section 8: Substance use disorders
48. Substance use disorders and the mechanisms of drug addiction • Trevor W. Robbins and Barry J. Everitt
49. Genetics of substance use disorders • Yann Le Strat, Nicolas Ramoz, and Philip Gorwood
50. Alcohol use disorder • Wim van den Brink and Falk Kiefer
51. Opioids: heroin, methadone, and buprenorphine • Michael Farrell, Briony Larance, and Courtney Breen
52. Cannabis and mental illness • David J. Castle
53. Stimulants, ecstasy, and other ‘party drugs’ • Adam R. Winstock and Remy Flechais
54. Psychedelics and dissociative substances • Adam R. Winstock and James Rucker
55. Tobacco addiction • Marcus Munafò and Meryem Grabski
56. Co-morbidity of substance use and psychiatric disorders • Julia M. A. Sinclair and Anne Lingford- Hughes
Section 9: Schizophrenia and psychotic disorders
57. The core dimensions of schizophrenia • Nancy C. Andreasen
58. Epidemiology and course of schizophrenia • Assen Jablensky
59. Genetics of schizophrenia • Kimberley M. Kendall, James T. R. Walters, and Michael C.O’Donovan
60. Structural and functional neuroimaging of schizophrenia • Andreea O. Diaconescu, Sandra Iglesias, and Klaas E. Stephan
61. Schizoaffective and schizotypal disorders/acute and transient psychotic disorders • William S. Stone, Stephen V. Faraone, and Ming T. Tsuang
62. Delusional disorders • Andreas Marneros
63. Prevention and early intervention in psychotic disorders • Emre Bora, Mahesh Jayaram, and Christos Pantelis
64. Antipsychotic and anticholinergic drugs • Herbert Y. Meltzer and William V. Bobo
65. The treatment and management of patients with schizophrenia • Joseph P. McEvoy, Kammarauche Asuzu, Daniel W. Bradford, Oliver Freudenreich, and Katherine H. Moyer
Section 10: Mood disorders
66. Diagnosis, classification, and differential diagnosis of mood disorders • S. Nassir Ghaemi and Sivan Mauer
67. Epidemiology of mood disorders • Lars Vedel Kessing
68. Primary prevention of mood disorders: building a target for prevention strategies • Gin S. Malhi
Section 11: Bipolar disorder
69. Basic mechanisms of and treatment targets for bipolar disorder • Grant C. Churchill, Nisha Singh, and Michael J. Berridge
70. Genetics of bipolar disorder • Francis J. McMahon and Sevilla Detera-Wadleigh
71. Neuroimaging of bipolar disorder • Mary L. Phillips and Wayne C. Drevets
72. Management and treatment of bipolar disorder • Eduard Vieta, Isabella Pacchiarotti, and David J. Miklowitz
73. Perinatal psychiatry • Ian Jones and Arianna Di Florio
Section 12: Depressive disorders
74. Basic mechanisms of and treatment targets for depressive disorders • Marcela Pereira, Roberto Andreatini, and Per Svenningsson
75. Genetic epidemiology of depression in the molecular era • Alison K. Merikangas and Kathleen R. Merikangas
76. Imaging of depressive disorders • Guy M. Goodwin and Michael Browning
77. Management and treatment of depressive disorders • Philip J. Cowen
Section 13: Trauma- and stress-related and adjustment disorders
78. Classification and descriptive psychopathology of post- traumatic stress disorder and other stressor-related disorders • Dean G. Kilpatrick, Matthew J. Friedman, and Amanda K. Gilmore
79. Basic mechanisms of, and treatment targets for, stress-related disorders • Bruce S. McEwen
80. Genetics of stress-related disorders • Michael G. Gottschalk and Katharina Domschke
81. Imaging of stress-related disorders • Navneet Kaur, Cecilia A. Hinojosa, Julia Russell, Michael B. VanElzakker, and Lisa M. Shin
82. Primary prevention and epidemiology of trauma- and stress-related disorders • Maria Bragesjö, Emily A. Holmes, Filip K. Arnberg, and Erik M. Andersson
83. Management and treatment of stress-related disorders • Leigh van den Heuvel and Soraya Seedat
84. Bereavement • Beverley Raphael†, Sally Wooding, and Julie Dunsmore
85. Recovered memories and false memories • Deborah Davis and Elizabeth F. Loftus
Section 14: Anxiety disorders
86. Core dimensions of anxiety disorders • Nastassja Koen and Dan J. Stein
87. Basic mechanisms, genetics, targets, and animal models for anxiety disorders • Martien J. Kas and Berend Olivier
88. Epidemiology of anxiety disorders • Hans-Ulrich Wittchen and Katja Beesdo-Baum
89. Genetics of anxiety disorders • Michael G. Gottschalk and Katharina Domschke
90. Neuroimaging of anxiety disorders • Gregor Leicht and Christoph Mulert
91. The primary prevention of anxiety disorders • Aliza Werner-Seidler, Jennifer L. Hudson, and Helen Christensen
92. Treatment of anxiety disorders • David S. Baldwin and Nathan T. M. Huneke
Section 15: Obsessive–compulsive and related disorders
93. Core dimensions of obsessive–compulsive disorder • Sophie C. Schneider, Eric A. Storch, and Wayne K. Goodman
94. Basic mechanisms of, and treatment/planning targets for obsessive–complusive disorder • Eric Burguière and Luc Mallet
95. Obsessive–compulsive disorder • Lior Carmi, Naomi A. Fineberg, Oded Ben Arush, and Joseph Zohar
96. Genetics of obsessive–compulsive disorder • Gerald Nestadt and Jack Samuels
97. Imaging of obsessive– compulsive disorder • Rebbia Shahab and Emily R. Stern
98. Management and treatment of obsessive–compulsive disorder • Naomi A. Fineberg, Lynne M. Drummond, Jemma Reid, Eduardo Cinosi, Lior Carmi, and Davis N. Mpavaenda
99. Hoarding disorder • Lorena Fernández de la Cruz and David Mataix-Cols
100. Body dysmorphic disorder • Megan M. Kelly and Katharine A. Phillips
Section 16: Feeding, eating, and metabolic disorders
101. The eating disorders • Christopher G. Fairburn and Rebecca Murphy
102. Basic mechanisms and potential for treatment of weight and eating disorders • Johannes Hebebrand, Jochen Antel, and Beate Herpertz-Dahlmann
103. Epidemiology and primary prevention of feeding and eating disorders • Katherine A Halmi
104. Genetics of feeding and eating disorders • Christopher Hübel, Cynthia M. Bulik, and Gerome Breen
105. Imaging of feeding and eating disorders • Natalie Kurniadi, Christina E. Wierenga, Laura A. Berner,a nd Walter H. Kaye
106. Management and treatment of feeding and eating disorders • Susan L. McElroy, Anna I. Guerdjikova, Nicole Mori, Paul L. Houser, and Paul E. Keck, Jr.
107. Aetiology and management of obesity • Jamie Hartmann-Boyce, Nerys M. Astbury, and Susan A. Jebb
108. Elimination disorders in children and adolescents • Alexander von Gontard
Section 17: Sleep–wake disorders
109. Basic mechanisms of, and possible treatment targets for, sleep–wake disorders • David Pritchett, Angus S. Fisk, Russell G. Foster, and Stuart N. Peirson
110. Diagnosis of sleep and circadian rhythm disorder • Kirstie N. Anderson
111. Epidemiology of sleep–wake and primary prevention of its disorders • Lena Katharina Keller, Eva C. Winnebeck, and Till Roenneberg
112. Genetics of sleep–wake disorders • Diego R. Mazzotti, Allan I. Pack, and Philip R. Gehrman
113. Multimodal imaging of sleep–wake disorders • Umberto Moretto, Dylan Smith, Liliana Dell’Osso, and Thien Thanh Dang- Vu
114. Management of insomnia and circadian rhythm sleep–wake disorders • Simon D. Kyle, Alasdair L. Henry, and Colin A. Espie
Section 18: Gender dysphoria and sexual dysfunction
115. The sexual dysfunctions and paraphilias • Cynthia A. Graham and John Bancroft
116. Gender dysphoria • Els Elaut and Gunter Heylens
Section 19: Personality disorders
117. Core dimensions of personality pathology • Andrew E. Skodol and Leslie C. Morey
118. Basic mechanisms of, and treatment planning/targets for, personality disorders • Kate E. A. Saunders and Steve Pearce
119. Personality disorders: epidemiology and clinical course • Renato D. Alarcón and Brian A. Palmer
120. Genetics of personality disorders • C. Robert Cloninger
121. Imaging of personality disorders • Christian Paret and Christian Schmahl
122. Treatment and management of personality disorder • Giles Newton-Howes and Roger Mulder
Section 20: Impulse-control and conduct disorders
123. Impulse-control and its disorders, including pathological gambling • Donald W. Black
124. Conduct disorders and antisocial personality disorder in childhood and adolescence • Stephen Scott and Melanie Palmer
Section 21: Suicide
125. Epidemiology and causes of suicide • Merete Nordentoft, Trine Madsen, and Annette Erlangsen
126. Self-harm: epidemiology and risk factors • Nav Kapur, Sarah Steeg, and Adam Moreton
127. Biological aspects of suicidal behaviour • J. John Mann and Dianne Currier
128. Prevention of suicide and treatment following self-harm • Keith Hawton, Kate E. A. Saunders, and Alexandra Pitman
Section 22: Somatic symptoms and related disorders
129. Deconstructing dualism: the interface between physical and mental illness • Michael Sharpe and Jane Walker
130. Neural mechanisms in chronic pain relevant for psychiatric interventions • Chantal Berna and Irene Tracey
131. Treatment of fibromyalgia (chronic widespread pain) and chronic fatigue syndrome • Jonathan Price
132. Factitious disorder and malingering • Thomas Merten and Harald Merckelbach
133. Functional neurological symptom disorder (conversion disorder) • Jon Stone and Michael Sharpe
Section 23: Service provision
134. Public policy and service needs in mental health • Martin Knapp
135. Planning and providing mental health services for a community • Tom Burns and Tony Kendrick
136. Health economic analysis of service provision • Judit Simon
137. Organization of psychiatric services for general hospital departments: proactive and preventive interventions in psychiatry • William H. Sledge and Julianne Dorset
138. Refugees and populations exposed to mass conflict • Mina Fazel, Susan Rees, and Derrick Silove
Section 24: Forensic psychiatry
139. Associations between psychiatric disorder and offending • Seena Fazel and Mark Toynbee
140. Developmental approach to understanding the needs of young people in contact with the criminal justice system • Sue Bailey and Prathiba Chitsabesan
141. Child molesters and other sexual offenders • Stephen J. Hucker
142. Stalking and querulous behaviour • Rosemary Purcell and Paul E. Mullen
143. Domestic violence and abuse and mental health • Louise M. Howard and Deirdre MacManus
144. Assessing and managing the risk of violence to others • Alec Buchanan
145. The expert witness in the criminal and civil courts • John O’Grady
146. Homicide • Matthew Large and Olav Nielssen
Index
