Neurology of Cognitive and Behavioral Disorders

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This reference text provides an insightful and unified synthesis of cognitive neuroscience and behavioral neurology. The strong clinical emphasis and outstanding illustrations will provide neurologists, psychiatrists, neuropsychologists, and psychologists with a solid foundation to the major neurobehavioral syndromes. With backgrounds in behavioral neurology, functional imaging and cognitive neuroscience, the two authors are in an ideal position to cover the anatomy, genetics, physiology, and cognitive neuroscience underlying these disorders. Their emphasis on therapy makes the book a "must read" for anyone who cares for patients with cognitive and behavioral disorders.

Author(s): Orrin Devinsky, Mark D'Esposito
Edition: 1
Year: 2001

Language: English
Pages: 472

CONTENTS......Page 12
OVERVIEW OF BRAIN ANATOMY......Page 20
Macroscopic Anatomy......Page 29
Cortical Connections......Page 30
Localization of Cognitive–Behavioral Function......Page 38
Cognitive–Behavioral Observation......Page 40
Testing Cognitive–Behavioral Abilities......Page 44
NEUROPSYCHOLOGICAL TESTING......Page 46
Intelligence......Page 50
Attention......Page 53
Memory and Learning......Page 54
Language......Page 55
Visuospatial Function......Page 56
Executive Function......Page 57
Personality, Mood, and Other Psychiatric Traits......Page 59
SUMMARY......Page 62
APPENDIX A: The Mental Status Examination......Page 68
APPENDIX B: A Brief but Sensitive Mental Status Examination......Page 69
2. FUNCTIONAL NEUROIMAGING OF COGNITION......Page 71
INFERENCE IN FUNCTIONAL NEUROIMAGING STUDIES OF COGNITIVE PROCESSES......Page 72
PRINCIPLES OF FUNCTIONAL MAGNETIC RESONANCE IMAGING......Page 74
Blocked Designs......Page 76
Event-Related Designs......Page 77
Statistical Errors......Page 78
Types of Hypothesis Tested by Functional Magnetic Resonance Imaging......Page 79
Presurgical Planning and Prognosis......Page 82
SUMMARY......Page 83
3. THE RIGHT HEMISPHERE, INTERHEMISPHERIC COMMUNICATION, AND CONSCIOUSNESS......Page 87
Constructional Praxis......Page 90
Relation of the Self to the Environment......Page 93
Body Schema and Disorders of the Corporeal Self......Page 94
RIGHT HEMISPHERE DOMINANCE OF THE PSYCHIC SELF......Page 97
Primary and Secondary Emotions......Page 98
Emotional Expression......Page 99
Emotional Cognition and Memory......Page 100
Volition......Page 101
Disorders of the Social Self......Page 102
Conversion Disorder......Page 104
Callosotomy and Functional Impairment......Page 106
Callosotomy and Consciousness......Page 108
The Modular Mind......Page 109
Cognitive Aspects of Consciousness......Page 110
SUMMARY......Page 113
Arousal and Alerting Network......Page 122
Orienting Network......Page 129
Selective Attentional Network......Page 130
RECOVERY......Page 133
Therapeutic Remediation of Neglect......Page 135
SUMMARY......Page 137
PERCEPTUAL AWARENESS......Page 141
Anatomy and Function of Cortical Visual Areas......Page 142
Cortical Visual Disorders and Defects......Page 151
Anatomy and Function of Cortical Auditory Areas......Page 170
Cortical Auditory Disorders......Page 171
Cortical Somatosensory Disorders......Page 175
SUMMARY......Page 177
ANATOMICAL AND PHYSIOLOGICAL ASPECTS OF LANGUAGE......Page 185
Cognitive–Linguistic Concepts......Page 186
Linguistic Components......Page 187
HEMISPHERIC HAND AND LANGUAGE DOMINANCE......Page 188
Handedness......Page 189
APHASIA......Page 190
Diagnosis of Aphasia......Page 192
Localization and Clinical Patterns of Aphasia......Page 195
Other Aphasias and Language Disorders......Page 217
Therapy for Aphasia......Page 223
AGRAPHIA......Page 224
Aphasic Agraphia......Page 225
GERSTMANN'S SYNDROME......Page 228
Finger Agnosia......Page 229
NONAPHASIC (NONLINGUISTIC) SPEECH DISORDERS......Page 230
Dysarthria......Page 231
Palilalia......Page 233
Mutism......Page 234
SUMMARY......Page 235
CORTICAL ANATOMY OF THE MOTOR SYSTEM......Page 245
Primary Motor Cortex......Page 247
Limbic Motor Areas......Page 248
Apraxia......Page 254
Basal Ganglia......Page 258
Parallel Cortical–Subcortical Circuits......Page 261
Direct and Indirect Motor Circuits......Page 262
SUBCORTICAL MOTOR CONTROL DISORDERS......Page 263
Emotional Incontinence and Pseudobulbar Palsy......Page 264
Degenerative and Other Basal Ganglia Disorders......Page 265
Functional Anatomy......Page 278
SUMMARY......Page 281
Short-Term and Long-Term Memory......Page 294
Episodic Memory......Page 295
Semantic Memory......Page 301
Procedural Memory......Page 303
MEMORY DYSFUNCTION PATTERNS IN NEUROLOGICAL DISORDERS......Page 304
Acute Memory Disorders......Page 305
Chronic Memory Disorders......Page 306
Pharmacological Therapy......Page 311
Cognitive Remediation Therapy......Page 313
SUMMARY......Page 314
ANATOMY OF THE FRONTAL LOBES......Page 321
Motor and Premotor Cortex......Page 322
Prefrontal Cortex......Page 323
Behavior and the Prefrontal Cortex......Page 324
Cognition and the Prefrontal Cortex......Page 327
Neurological Deficits and the Prefrontal Cortex......Page 331
Orbitofrontal Circuit......Page 332
Medial Frontal Circuit......Page 334
ROLE OF DOPAMINE IN FRONTAL LOBE FUNCTION......Page 335
Traumatic Brain Injury......Page 337
Epilepsy......Page 339
ASSESSMENT OF EXECUTIVE FUNCTION......Page 342
SUMMARY......Page 344
THEORIES AND SYSTEMS OF EMOTION......Page 349
Peripheral and Central Theories of Emotion......Page 350
Relation of Emotion and Limbic Systems......Page 352
Subcortical Limbic Areas......Page 353
Amygdala......Page 354
Anterior Cingulate Cortex......Page 361
Posterior Orbitofrontal Cortex......Page 364
HEMISPHERIC CONTRIBUTIONS TO EMOTION......Page 369
BRAIN DISORDERS AND EMOTIONAL CHANGES......Page 370
Epilepsy......Page 371
SUMMARY......Page 381
11. THERAPY FOR COGNITIVE AND NEUROBEHAVIORAL DISORDERS......Page 391
THERAPY: THE BIG PICTURE......Page 392
Physical and Occupational Therapy......Page 394
Pragmatic Therapeutic Approaches......Page 395
Depression......Page 397
Anxiety......Page 405
Psychosis......Page 407
Impulsivity......Page 408
Tricyclic Antidepressants......Page 409
Selective Serotonin Reuptake Inhibitors......Page 411
Bupropion......Page 415
Monoamine Oxidase Inhibitors......Page 416
Antipsychotic drugs......Page 417
Central Nervous System Stimulants......Page 419
Sedative–Hypnotic and Anxiolytic Drugs......Page 421
Antiepileptic Drugs......Page 423
Cognition Enhancers......Page 430
Antioxidants......Page 432
Herbs and Dietary Supplements......Page 433
Vagus Nerve Stimulation......Page 434
Insomnia......Page 435
Delirium......Page 436
SUMMARY......Page 437
A......Page 446
B......Page 449
C......Page 450
D......Page 452
E......Page 454
F......Page 455
G......Page 456
H......Page 457
L......Page 458
M......Page 459
N......Page 461
O......Page 462
P......Page 463
R......Page 465
S......Page 466
T......Page 468
V......Page 469
Z......Page 470