Neurology and Clinical Neuroscience

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This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available. From Alzheimer's disease to vestibular system disorders, you'll find the practical guidance you need to diagnose effectively and provide an appropriate therapeutic approach for each individual case. Plus, a templated, four-color design offers you easy access to pertinent informationIntegrates basic science with clinical neurology to help you better understand neurologic diseases and provide the most accurate diagnosis and best treatment plan for each patient.Discusses the latest research results and offers new information on treatment options.Features the expertise of international authorities, providing a worldwide perspective.Includes a CD-ROM image bank of the text's illustrations downloadable into PowerPoint?® presentations.Uses a templated, four-color format that makes information accessible and easy to understand-particularly the basic science concepts.

Author(s): Anthony H. V. Schapira DSc MD FRCP FMedSci
Publisher: Mosby
Year: 2006

Language: English
Pages: 1664

Cover......Page 1
Copyright......Page 2
Dedication......Page 3
CONTRIBUTORS......Page 8
PREFACE......Page 20
1 CLINICAL ASSESSMENT OF MENTAL STATUS......Page 22
2 PRINCIPLES OF NEUROPSYCHOMETRIC ASSESSMENT......Page 42
3 DISORDERS OF LANGUAGE......Page 51
4 DISORDERS OF MEMORY......Page 63
5 HIGHER VISUOPERCEPTUAL DISORDERS AND DISORDERS OF SPATIAL COGNITION......Page 79
6 THE NEGLECT SYNDROME......Page 93
7 EXECUTIVE FUNCTION AND ITS ASSESSMENT......Page 103
8 COMA AND BRAIN DEATH......Page 117
9 THE PERSISTENT VEGETATIVE STATE (PROLONGED POSTCOMA UNRESPONSIVENESS) AND POSTHYPOXIC BRAIN INJURY......Page 137
10 AUTISM AND ATTENTION DEFICIT/HYPERACTIVITY DISORDER......Page 149
11 DELIRIUM......Page 161
12 MOTOR SPEECH AND SWALLOWING DISORDERS......Page 175
13 DISORDERS OF SMELL AND TASTE......Page 191
Section II: Sleep and Sleep Disorders......Page 199
14 THE PHYSIOLOGY OF SLEEP......Page 200
15 PRIMARY DISORDERS OF SLEEP......Page 205
16 SLEEP APNEA......Page 223
17 TOURETTE’S SYNDROME, TICS AND OBSESSIVE-COMPULSIVE DISORDERS......Page 234
18 SCHIZOPHRENIA AND SCHIZOPHRENIA-LIKE PSYCHOSIS......Page 243
19 AFFECTIVE DISORDERS......Page 255
20 CONVERSION AND DISSOCIATION SYNDROMES......Page 269
21 EXAMINATION OF THE VISUAL SYSTEM......Page 280
22 GENETIC CAUSES OF BLINDNESS......Page 294
23 OPTIC NEUROPATHIES......Page 305
24 RETINAL DISEASE......Page 315
25 EXAMINATION OF HEARING AND BALANCE......Page 338
26 AUDITORY SYSTEM DISORDERS......Page 349
27 VESTIBULAR SYSTEM DISORDERS......Page 357
28 ORTHOSTATIC HYPOTENSION......Page 374
29 BLADDER AND SEXUAL FUNCTION AND DYSFUNCTION......Page 382
30 PRIMARY AUTONOMIC FAILURE......Page 392
31 ORGANIZATION: PYRAMIDAL AND EXTRAPYRAMIDAL SYSTEM......Page 416
32 APRAXIA......Page 422
33 TREMOR......Page 437
34 MYOCLONUS......Page 455
35 DYSTONIA......Page 463
36 GAIT DISTURBANCES AND FALLS......Page 475
37 RESTLESS LEGS SYNDROME......Page 491
38 SPINE AND SPINAL CORD: DEVELOPMENTAL DISORDERS......Page 508
39 PRIMARY MYELOPATHIES (DEGENERATIVE, INFECTIVE, METABOLIC)......Page 527
40 SPINAL DISEASE: NEOPLASTIC,DEGENERATIVE, AND INFECTIVE SPINAL CORD DISEASES AND SPINAL CORD COMPRESSION......Page 531
41 ANATOMY AND PHYSIOLOGY OF CEREBRAL AND SPINAL CORD CIRCULATION......Page 560
42 ISCHEMIC STROKE: MECHANISMS, EVALUATION, AND TREATMENT......Page 571
43 INTRACRANIAL HEMORRHAGE: ANEURYSMAL, IDIOPATHIC, AND HYPERTENSIVE......Page 607
44 ARTERIOVENOUS MALFORMATIONS OF THE BRAIN AND SPINAL CORD......Page 615
45 PROTHROMBOTIC STATES AND RELATED CONDITIONS......Page 629
46 CEREBRAL VENOUS THROMBOSIS......Page 641
47 VASCULAR DEMENTIA......Page 655
48 REHABILITATION AFTER STROKE......Page 665
49 DEVELOPMENTAL DEFECTS AND PATHOPHYSIOLOGY......Page 682
50 CLINICAL SPECTRUM......Page 693
51 GENETICS OF EPILEPSY......Page 701
52 ASSESSMENT AND MANAGEMENT PRINCIPLES......Page 711
53 DRUG TREATMENT......Page 727
54 MANAGEMENT OF STATUS EPILEPTICUS......Page 739
55 HEADACHE PATHOGENESIS......Page 754
56 MIGRAINE......Page 759
57 TENSION-TYPE HEADACHE......Page 777
58 CHRONIC DAILY HEADACHE......Page 783
59 TRIGEMINAL AUTONOMIC CEPHALALGIAS: CLUSTER HEADACHE AND RELATED CONDITIONS......Page 793
60 OTHER SECONDARYHEADACHE DISORDERS......Page 813
61 IDIOPATHIC INTRACRANIAL HYPERTENSION......Page 827
62 LOW CEREBROSPINAL FLUID HEADACHE......Page 837
63 HYDROCEPHALUS, INCLUDING NORMAL-PRESSURE HYDROCEPHALUS......Page 845
64 TRIGEMINAL NEURALGIA AND OTHER FACIAL PAIN......Page 855
65 ALZHEIMER’S DISEASE......Page 866
66 AMYOTROPHIC LATERAL SCLEROSIS......Page 879
67 HUNTINGTON’S DISEASE......Page 899
68 INHERITED ATAXIAS......Page 907
69 HEREDITARY SPASTIC PARAPLEGIAS*......Page 919
70 DEMENTIA WITH LEWY BODIES......Page 931
71 PARKINSON’S DISEASE......Page 947
72 PARKINSON PLUS DISORDERS......Page 981
73 FRONTOTEMPORAL DEMENTIA......Page 1003
74 EPIDEMIOLOGY AND GENETICS OF MULTIPLE SCLEROSIS......Page 1016
75 PATHOPHYSIOLOGY OF MULTIPLE SCLEROSIS: DEMYELINATION AND AXONAL INJURY......Page 1022
76 CLINICAL SPECTRUM: DEFINITION AND NATURAL PROGRESSION......Page 1035
77 INVESTIGATIONS IN MULTIPLE SCLEROSIS......Page 1051
78 TREATMENT OF MULTIPLE SCLEROSIS......Page 1065
79 ACUTE DISSEMINATED ENCEPHALOMYELITIS AND PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY......Page 1077
80 THE LEUKODYSTROPHIES......Page 1085
81 ANATOMY AND PHYSIOLOGY OF MUSCLE AND NERVE......Page 1114
82 INHERITED NEUROPATHIES......Page 1119
83 METABOLIC, IMMUNE-MEDIATED, AND TOXIC NEUROPATHIES......Page 1133
84 INFECTIVE NEUROPATHIES......Page 1147
85 MUSCULAR DYSTROPHIES......Page 1162
86 THE CONGENITAL MYOPATHIES......Page 1188
87 CHANNELOPATHIES OF MUSCLE (INCLUDING THE MYOTONIC DYSTROPHIES)......Page 1207
88 METABOLIC MYOPATHIES (INCLUDING MITOCHONDRIAL DISEASES)......Page 1215
89 INFLAMMATORY MYOPATHIES......Page 1231
90 NEUROMUSCULAR JUNCTION DISORDERS......Page 1243
91 BACTERIAL MENINGITIS......Page 1256
92 VIRAL MENINGITIS AND ENCEPHALITIS......Page 1269
93 NEUROLOGICAL DISORDERS ASSOCIATED WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION......Page 1281
94 PARASITIC AND FUNGAL INFECTIONS......Page 1293
95 PRION DISEASES......Page 1317
96 NEUROSARCOIDOSIS AND NEURO-BEHÇET’S DISEASE......Page 1323
97 THE NEUROLOGICAL VASCULITIDES......Page 1333
98 TUMORS OF THE BRAIN......Page 1344
99 TUMORS OF THE SPINAL CORD......Page 1361
100 NEUROLOGICAL COMPLICATIONS OF CANCER TREATMENTS......Page 1373
101 PARANEOPLASTIC DISORDERS OF THE NERVOUS SYSTEM......Page 1381
102 TUMORS OF THE PERIPHERAL NERVES......Page 1395
103 HEAD TRAUMA......Page 1406
104 SPINAL TRAUMA......Page 1417
105 PERIPHERAL NERVE INJURY......Page 1429
106 NEUROREHABILITATION......Page 1443
107 ENCEPHALOPATHIES......Page 1454
108 WILSON DISEASE......Page 1467
109 VITAMIN DEFICIENCIES AND OTHER NUTRITIONAL DISORDERS OF THE NERVOUS SYSTEM......Page 1475
110 UREA CYCLE DISORDERS......Page 1489
111 ENVIRONMENTAL TOXINS AND DISORDERS OF THE NERVOUS SYSTEM......Page 1497
112 NEUROLOGY OF PREGNANCY AND THE PUERPERIUM......Page 1510
113 NEUROLOGY OF CARDIOLOGY......Page 1525
114 NEUROLOGY OF GASTROENTEROLOGY AND HEPATOLOGY......Page 1531
115 NEUROLOGY OF HEMATOLOGY......Page 1545
116 NEUROLOGY OF COMMON ELECTROLYTE DISORDERS......Page 1553
117 NEUROLOGY OF DRUG AND ALCOHOL ADDICTIONS......Page 1557
118 NEUROLOGY OF ENDOCRINOLOGY......Page 1565
119 NEUROLOGY OF RHEUMATOLOGY,IMMUNOLOGY, AND TRANSPLANTATION......Page 1577
120 NEUROLOGY OF PULMONOLOGY AND ACID-BASE DISTURBANCE......Page 1589
121 NEUROLOGY OF CEREBRAL PALSY......Page 1597
INDEX......Page 1603