The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach.- Phosphodiesterase Inhibition to Target the Synaptic Dysfunction in Alzheimer’s Disease.- Glutamate and Neurodegenerative Disease.- Modulation of the Kynurenine Pathway for the Potential Treatment of Neurodegenerative Diseases.- Spinal Muscular Atrophy: Current Therapeutic Strategies
Author(s): Roland W. Bürli, Elizabeth Thomas, Vahri Beaumont (auth.), Celia Dominguez (eds.)
Series: Topics in Medicinal Chemistry 6
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2010
Language: English
Pages: 196
Tags: Medicinal Chemistry; Neurology; Pharmacology/Toxicology
Front Matter....Pages i-xvii
The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach....Pages 1-56
Phosphodiesterase Inhibition to Target the Synaptic Dysfunction in Alzheimer’s Disease....Pages 57-90
Glutamate and Neurodegenerative Disease....Pages 91-147
Modulation of the Kynurenine Pathway for the Potential Treatment of Neurodegenerative Diseases....Pages 149-176
Spinal Muscular Atrophy: Current Therapeutic Strategies....Pages 177-191
Back Matter....Pages 193-196