This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.
Written by world-renowned scientists in the field, Neural Stem Cells in Development, Adulthood and Disease presents cutting-edge studies of interest to both established neurogenesis researchers and readers with general interests in nervous system science. It is an authoritative addition to the Stem Cell Biology and Regenerative Medicine series.
Author(s): H. Georg Kuhn, Amelia J. Eisch (eds.)
Series: Stem Cell Biology and Regenerative Medicine
Edition: 1
Publisher: Humana Press
Year: 2015
Language: English
Pages: 202
Tags: Stem Cells; Neurosciences; Developmental Biology
Front Matter....Pages i-xxi
Adult Neurogenesis and Regeneration: Focus on Nonmammalian Vertebrates....Pages 1-21
Differential Intrinsic and Extrinsic Regulations of the Two Adult Neurogenic Regions....Pages 23-40
The Role of Adult-Born Dentate Granule Neurons in the Regulation of Mood....Pages 41-52
Stem Cells and Neurogenesis in Relation to Dementia and Alzheimer’s Disease Mouse Models....Pages 53-78
Hippocampal Neurogenesis in Neurodegenerative Movement Disorders....Pages 79-105
Linking Adult Neurogenesis to Epilepsy Through Epigenetics....Pages 107-118
Activity-Based Maintenance of Adult Hippocampal Neurogenesis: Maintaining a Potential for Lifelong Plasticity....Pages 119-123
Neural Stem Cells and Demyelinating Disease....Pages 125-153
Stem Cell-Based Therapies for Spinal Cord Regeneration....Pages 155-174
Direct Reprogramming of Somatic Cells into Induced Neuronal Cells: Where We Are and Where We Want to Go....Pages 175-195
Back Matter....Pages 197-202
