Neoplastic Hematopathology: Experimental and Clinical Approaches

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Fulfilling the void with a Hematopathology book that integrates clinical and experimental studies with diagnostic criteria, Neoplastic Hematopathology: Experimental and Clinical Approaches provides an overview of the discipline of hematopathology that connects the field with recent advances in immunology research and current clinical practice in the treatment of lymphomas and leukemias. Designed for both trainees and specialists in pathology and hematology-oncology, Neoplastic Hematopathology: Experimental and Clinical Approaches has separate sections on laboratory techniques, diagnostic hematopathology, treatment and stem cell transplantation. Expert chapter authors address both myeloid and lymphoid tumors, and provide much needed coverage in transplant biology. A study guide highlights key chapter points, making the text suitable for boards review in hematopathology and hematology-oncology.

Author(s): Dan Jones (auth.), Dan Jones (eds.)
Series: Contemporary Hematology
Edition: 1
Publisher: Humana Press
Year: 2010

Language: English
Pages: 644
Tags: Pathology; Hematology; Oncology; Internal Medicine

Front Matter....Pages i-xv
Front Matter....Pages 1-1
Approaches to Classification of Lymphoma and Leukemia....Pages 3-20
Immunohistochemical Profiling of Lymphoma....Pages 21-44
Flow Cytometry in the Evaluation of Hematologic Malignancies....Pages 45-59
Molecular Diagnostics and Cytogenetic Testing....Pages 61-95
Front Matter....Pages 98-98
The Bone Marrow in Normal and Disease States....Pages 99-121
Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms....Pages 123-144
Acute Myeloid Leukemia....Pages 145-163
Treatment of Acute Myeloid Leukemia and Myelodysplastic Syndromes....Pages 165-176
Myeloproliferative Neoplasms....Pages 177-192
Chronic Myelogenous Leukemia....Pages 193-211
Treatment of Myeloproliferative Neoplasms....Pages 213-220
Front Matter....Pages 222-222
Lymph Node Biology and Lymphadenitis....Pages 223-237
Lymphoblastic Leukemia and Lymphoma....Pages 239-250
Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma....Pages 251-261
Marginal Zone Lymphomas....Pages 263-278
Follicular Lymphoma and Mantle Cell Lymphoma....Pages 279-301
Aggressive B-cell Lymphomas: Diffuse Large B-cell Lymphoma and Burkitt Lymphoma....Pages 303-322
Therapy of B-cell Lymphoproliferative Disorders....Pages 323-332
Plasma Cell Myeloma and Other Plasma Cell Dyscrasias....Pages 333-348
Hodgkin Lymphoma....Pages 349-366
Front Matter....Pages 222-222
Treatment of Hodgkin Lymphoma....Pages 367-389
Classification of T-cell and NK-cell Malignancies....Pages 391-412
Clinical Management of Non-cutaneous T-cell and NK-cell Malignancies....Pages 413-426
Cutaneous T-cell Lymphomas....Pages 427-447
Treatment of Cutaneous T-cell Lymphomas....Pages 449-457
Histiocytic and Dendritic Cell Neoplasms....Pages 459-475
Extranodal Lymphomas and Tumors of the Thymus....Pages 477-501
Front Matter....Pages 504-504
Clinical Aspects of Hematopoietic Stem Cell Transplantation....Pages 505-511
Post-transplant Molecular Monitoring....Pages 513-520
Post-transplant Immune Function and the Development of Lymphoma....Pages 521-527
Front Matter....Pages 530-530
Hematopoiesis and Stem Cell Biology....Pages 531-544
Role of Host Genetics in Lymphoma....Pages 545-552
Developing Prognostic Models for Diffuse Large B-cell Lymphoma....Pages 553-561
Growth Signaling and Survival Pathways in Aggressive B-cell Lymphoma....Pages 563-572
Proteomic Profiling and Target Identification in Lymphoma....Pages 573-582
Mouse Models of Lymphoma and Lymphoid Leukemia....Pages 583-596
Mouse Models of Myeloid Leukemia....Pages 597-610
Designing Targeted Therapies for Lymphomas and Leukemias....Pages 611-626
Back Matter....Pages 627-644