Glaxo Wellcome Research & Development, Herts, UK. Gives practical guidance in the process of extraction and isolation of natural products. Modifiedoutline format. Halftone graphs and illustrations. For researchers and scientists.
Author(s): Richard J. P. Cannell
Edition: 1
Year: 1998
Language: English
Pages: 475
Cover......Page 1
Contents......Page 2
1. How to Approach the Isolation of a Natural Product......Page 12
2. Initial Extraction and Product Capture......Page 63
3. Supercritical Fluid Methods......Page 100
4. Isolation by Low-Pressure Column Chromatography......Page 119
5. Isolation by Ion-Exchange Methods......Page 149
6. Isolation by Preparative HPLC......Page 173
7. Isolation by Planar Chromatography......Page 217
8. Separation by High-Speed Countercurrent Chromatography......Page 254
9. Crystallization and Final Stages of Purification......Page 267
10. Dereplication and Partial Identification of Natural Products......Page 285
11. Purification of Water-Soluble Natural Products......Page 334
12. Special Problems with the Extraction of Plants......Page 347
13. Isolation of Marine Natural Products......Page 368
14. Scale-Up of Natural Products Isolation......Page 412
15. Follow-Up of Natural Product Isolation......Page 428
Index......Page 467
