The recent literature on whole genome sequences provides abundant evidence for the action of natural genetic engineering in evolution. Discoveries about natural genetic engineering have coincided with rapid progress in our understanding of epigenetic control and RNA-directed chromatin formation. Special attention needs to be paid to the role of viruses and related so-called "parasitic" elements in the origin of genome formatting and natural genetic engineering capabilities especially the role of non-random genetic change operators in the production of complex evolutionary inventions. These Proceedings of the Symposium “Natural Genetic Engineering and Natural Genome Editing” (3-6 July 2008, Salzburg, Austria) assemble scientists working on genome organization, genome restructuring, genome formatting and virus research to discuss how to integrate these discoveries into the basic understanding of evolution, development and disease.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Author(s): Günther Witzany
Edition: 1
Publisher: Wiley-Blackwell
Year: 2009
Language: English
Pages: 320
Introduction : A Perspective on Natural Genetic Engineering and Natural Genome Editing......Page p1
Part V. Epigenetic Control......Page p000
6 Revisiting the Central Dogma in the 21st Century......Page p6
29 Deconstructing the Dogma : A New View of the Evolution & Genetic Programming.........Page p29
47 On the Origin of Cells and Viruses: Primordial Virus World Scenario......Page p47
65 Billion-year War between...(Cells and Viruses) the Major Source of Novelty......Page p65
78 Learning from Bacteria about Natural Information Processing......Page p78
91 The Viral Eukaryogenesis Hypothesis: Viruses in the Emergence of Eukaryotes.........Page p91
106 Cell-Cell Channels, Viruses, and Evolution: ...Higher Levels of Complexity......Page p106
120 Impact of RNA Virus Infection on Plant Cell Function and Evolution......Page p120
129 Hen or Egg? : Some Thoughts on Tunneling Nanotubes......Page p129
137 Evolution of Genes and Organisms: Tree/Web of Life & Horiz. Gene Transfer......Page p137
146 The Natural Genetic Engineering of Polydnaviruses......Page p146
157 Friendly Viruses : Special Relationship, Endogenous Retroviruses & Host......Page p157
173 Nat. Gen. Engineering of Hep. C Virus NS5A for Immune System Counterattack......Page p173
186 The Fragmented Gene......Page p186
194 The Source of Self : Genetic Parasites and the Origin of Adaptive Immunity......Page p194
233 Cellular Genes Derived from Gypsy/Ty3 Retrotransposons in Mammalian Genomes......Page p233
244 Noncoding RNAs: Persistent Viral Agents as Modular Tools for Cellular Needs......Page p244
268 APOBEC3 Proteins Inhibit LINE-1 Retrotransposition, Absent ORF1p Binding......Page p268
276 Epigenetic Regulation of Mammalian Genomes by Transposable Elements......Page p276
285 Are There Epigenetic Controls in Trypanosoma cruzi?......Page p285
291 Conceptual and Methodological Biases in Network Models......Page p291
305 ...a Relational Viewpoint in a Complex Account of Living Systems......Page p305
318 Erratum for Ann. N. Y. Acad. Sci. 1171: 137-148......Page p318
319 Erratum for Ann. N. Y. Acad. Sci. 1171: 570-575......Page p319
