Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads. Some of the major classes of natural bioactive compounds include phenolics, alkaloids, tannins, saponins, lignin, glycosides, terpenoids, and many more. They possess a broad range of biological activities and are primarily useful in the treatment of various health issues. At the same time, the search for new and novel drugs is never-ending and, despite major advances in synthetic chemistry, nature remains an essential resource for drug discovery.
Therefore, more and more researchers are interested in understanding the chemistry, clinical pharmacology, and beneficial effects of bioactive compounds in connection with solving human health problems. This book presents a wealth of information on natural metabolites that have been or are currently being used as drugs or leads for the discovery of new drugs. In addition, it highlights the importance of natural products against various human diseases, and their applications in the drug, nutraceuticals, cosmetics and herbal industries. Accordingly, the book offers a valuable resource for all students, educators, and healthcare experts involved in natural product research, phytochemistry, and pharmacological research.
Author(s): Mallappa Kumara Swamy, Mohd Sayeed Akhtar
Publisher: Springer
Year: 2019
Language: English
Pages: 501
Front Matter ....Pages i-xx
Secondary Metabolites from Rosemary (Rosmarinus officinalis L.): Structure, Biochemistry and Therapeutic Implications Against Neurodegenerative Diseases (Sahir Sultan Alvi, Parvej Ahmad, Maleeha Ishrat, Danish Iqbal, M. Salman Khan)....Pages 1-24
The Role of Plant Metabolites in Drug Discovery: Current Challenges and Future Perspectives (Nooryasmin Anwar, Yong Kiat Teo, Joash Ban Lee Tan)....Pages 25-51
Current Insights on the Role of Terpenoids as Anticancer Agents: A Perspective on Cancer Prevention and Treatment (Irfan A. Ansari, Mohd Sayeed Akhtar)....Pages 53-80
Myristica fragrans Houtt.: Botanical, Pharmacological, and Toxicological Aspects (Greetha Arumugam, Boregowda Purushotham, Mallappa Kumara Swamy)....Pages 81-106
Coscinium fenestratum: A Review on Phytochemicals and Pharmacological Properties (Muhammad Taher, Mohamad Shahreen Amri, Deny Susanti, Muhammad Badri Abdul Kudos, Anis Natasha Shafawi, Soraya Nur Yazid)....Pages 107-125
Computationally Designed Recombinant-DNA-Based Compounds Production Driven in Plants During Secondary Metabolism and Their Implication in Antimalarial Therapies (Glaucia C. Pereira, Sonia Malik, Zoltan Kis, Brenda Rocamonde)....Pages 127-146
Curcumin-Loaded Nanoparticles and Their Potential as Anticancer Agents in Breast Cancer (Leanne De Silva, Bey-Hing Goh, Learn-Han Lee, Lay-Hong Chuah)....Pages 147-178
Techniques for Extraction, Isolation, and Standardization of Bio-active Compounds from Medicinal Plants (Mohammad Kamil Hussain, Mohammad Saquib, Mohammad Faheem Khan)....Pages 179-200
Phytotherapeutics: The Substitutes for Glioblastoma Multiforme (Megha Gautam, Sahil Srivastav, Niharika Tiwary, Shweta Dang, Reema Gabrani)....Pages 201-213
Cosmetic Potential of Natural Products: Industrial Applications (Mahesh Sreekantan Krishna, Fathima Jaseela, Veena Vijayan Girija)....Pages 215-250
Natural Compounds Extracted from Medicinal Plants and Their Applications in the Treatment of Diabetes and Hypertension (Pooja Rawat, Pawan Kumar Singh, Vipin Kumar)....Pages 251-274
Plant Metabolites as New Leads to Drug Discovery (Santanu Sasidharan, Prakash Saudagar)....Pages 275-295
Natural Compounds Extracted from Medicinal Plants and Their Applications in Cardiovascular and Kidney Diseases (Chetna Faujdar, Priyadarshini)....Pages 297-312
Therapeutic Potential of Plant Polyphenolics and Their Mechanistic Action Against Various Diseases (Rajeswari Ravindran, Mallappa Kumara Swamy, Ravindran Jaganathan)....Pages 313-351
Phytochemical Aspects of Medicinal Plants of Northeast India to Improve the Gynaecological Disorders: An Update (Suparna Lodh, Mallappa Kumara Swamy)....Pages 353-367
Bio-active Compounds from Unani Medicinal Plants and Their Application in Urolithiasis (Shaikh Ajij Ahmed Makbul, Nasreen Jahan, Mohd Afsahul Kalam)....Pages 369-407
Therapeutic Potential of Rhizomatous Plants Used in Unani Medicare System (Mohd Afsahul Kalam, Ghufran Ahmad, Anwar Shahzad, Shaikh Ajij Ahmad Maqbul, Mohd Sayeed Akhtar)....Pages 409-464
Extraction Techniques for Plant-Based Bio-active Compounds (Perihan Yolci Omeroglu, Büşra Acoglu, Tuğba Özdal, Canan Ece Tamer, Ömer Utku Çopur)....Pages 465-492
