Nanoreactors are nanoscale vehicles for enzymes and sensors that are used to create physical and chemical reactions. Nanoreactor developers are on the cusp of extraordinary advances in medical diagnostics and therapies, tissue engineering, and cell biology, and this authoritative resource puts bioengineers right at the cutting edge. This unique book offers first-of-its-kind coverage of nanoreactor design, providing full details on the research, practice, synthesis, and characterization of nanoreactors. It includes 14 actual systems explained by the pioneers who are developing them. This groundbreaking volume reviews the fundamentals of various nanoreactor configurations and addresses core design issues and challenges.
Author(s): Agnes Ostafin, Katharina Landfester
Series: Artech House engineering in medicine & biology
Edition: 1
Publisher: Artech House Publishers
Year: 2008
Language: English
Pages: 294
Contents......Page 6
1.1 What is a Nanoreactor?......Page 12
1.2 Examples of Nanoreactor Systems......Page 16
1.3 Conclusions......Page 33
Miniemulsion Droplets as Nanoreactors......Page 58
2.1 Different Kinds of Polymerization in the Nanoreactors......Page 60
2.2 Formation of Nanocapsules......Page 73
2.3 Crystallization in Miniemulsion Droplets......Page 82
2.4 Conclusion......Page 84
3.1 Introduction......Page 92
3.2 Construction, Shape Transformations, and Structural Modifications of Phospholipid Nanotube-Vesicle Networks......Page 94
3.3 Transport Phenomena in Nanotube-Vesicle Networks......Page 107
3.4 Chemical Reactions in Nanotube-Vesicle Networks......Page 117
3.5 Summary and Outlook......Page 133
4.1 Introduction......Page 144
4.2 The Mechanism of Self-Assembly of Mesoporous Materials......Page 146
4.3 Functionalization of the Pore Walls......Page 150
4.4 Controlling the Mesopore Diameter......Page 151
4.5 Characterization......Page 152
4.6 Protein Adsorption and Enzyme Activity......Page 154
4.7 Morphogenesis of Nanoand Microparticles......Page 158
4.8 Drug Delivery......Page 162
4.9 Bioactive Glasses for Tissue Engineering......Page 165
4.10 Summary......Page 166
5.1 Introduction......Page 172
5.2 Basic Design of a Nanoreactor for ROS Detection......Page 173
5.3 Synthesis of a Nanoreactor......Page 179
5.4 Characterization of a Synthesized Nanoreactor......Page 182
5.5 Detection of ROS with the Nanoreactor......Page 185
5.6 Reactive Oxygen Species (ROS) and Diseases......Page 189
5.7 Conclusions......Page 191
6.1 Introduction......Page 198
6.2 Conclusion......Page 216
Acknowledgements......Page 217
7.1 Enzymes and Disease......Page 220
7.2 Enzyme Therapy......Page 221
7.3 Summary......Page 234
Nanoractors in Stem Cell Research......Page 240
8.1 Stem Cells Are a Crucial Cell Population in Animal and Human Organisms......Page 241
8.2 (Stem) Cells as Nanoreactors......Page 243
8.3 The Concept of Stem Cells is Born: Definition of the Hematopoetic Stem Cell......Page 244
8.4 fiNewfl Stem Cell Typ......Page 247
8.5 Nanoreactors/Nanoparticles and Mammalian (Stem) Cells......Page 251
About the Editors......Page 280
Index......Page 284
