Nanopathology: The Health Impact of Nanoparticles

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Enormous funds are currently being invested in nanotechnology, yet very little is known about how its products and by-products can interfere with organisms, both end-users and people involved in their manufacture. Similar scenarios are already widely known in the history of science, such as the exploitation of radioactivity or the controversial issue of genetically modified organisms. As nanoparticles are more or less voluntarily produced, they are almost uncontrollably disseminated in the environment and in organisms, and thus constitute a growing concern. Describing the impact of nanoparticles (and microparticles) on human and animal health, this book offers the first criteria for preventing potential problems deriving from these particles.

Contents: How the Whole Thing Began or the Logic Path Towards a Discovery; In-Vitro and In-Vivo Biological Behavior of Micro and Nanoparticles; Clinical Cases: Lung, Blood, Liver, Kidney, Digestive System, Vessels, Sperm; Six Detective Stories ; War and Nanoparticles; Nanoparticles in the Environment and Working Places; Nanoparticles in Food, Cosmetics and Other Products; New York 9/11; The Future and Prevention Criteria.

Author(s): Antonietta M. Gatti, Stefano Montanari
Edition: 1
Publisher: Pan Stanford Publishing
Year: 2007

Language: English

Contents......Page 14
Acknowledgements......Page 8
Preface......Page 10
1. How the Whole Thing Began or the Logic Path Towards a Discovery......Page 16
1.1 Introduction......Page 21
1.2 Bibliography......Page 25
2.1 Introduction......Page 26
2.2.1 Dentistry......Page 28
2.2.2 Orthopaedics......Page 29
2.2.3 Nanostructured surfaces......Page 31
2.2.4 Drug delivery......Page 32
2.2.5 Nanomedicine......Page 34
2.3 The results of the nanopathology project......Page 37
2.3.1 In-vivo experiments......Page 43
2.4 Bibliography......Page 48
3.1 Introduction......Page 54
3.2 Lung......Page 57
3.3 Blood......Page 85
3.4 Liver......Page 95
3.5 Kidney and adrenal gland......Page 110
3.6 Digestive system......Page 117
3.7 Vessels......Page 129
3.8 Sperm......Page 130
3.9 A few considerations on reproduction......Page 136
3.10 Bibliography......Page 146
4.1 The 1st case......Page 150
4.2 The 2nd case......Page 157
4.3 The 3rd case......Page 160
4.4 The 4th case......Page 163
4.5 The 5th case......Page 167
4.6 The 6th case......Page 170
5. War and Nanoparticles......Page 176
5.1 Civilians living around a firing ground......Page 213
5.2 A few reflections......Page 214
5.3 Bibliography......Page 215
6.1 Introduction......Page 218
6.2 Chimneysweeps: a historical case......Page 220
6.3 Welding metals......Page 222
6.4 Toner......Page 225
6.5 The particulate active filter or FAP......Page 227
6.6 The environment around a foundry......Page 230
6.7 The environment around a power plant......Page 235
6.8 The case of a ship......Page 242
6.9 Incinerators......Page 243
6.10 Tobacco smoke......Page 246
6.11 Bibliography......Page 252
7. Nanoparticles in Food, Cosmetics and Other Products......Page 254
7.1 Bibliography......Page 264
8. New York 9/11......Page 266
8.1 Bibliography......Page 278
9.1 The state of the art......Page 280
9.2 What is next?......Page 282
9.3 The future......Page 295
9.4 A few reflections......Page 296
9.5 Bibliography......Page 299
Appendix......Page 302
Index......Page 306