Nanomedicine From Science to Business

Content: Dedication Purpose Table of Contents Introduction What is Nanomedicine? What is Translational Medicine? What is Innovation? What is Intellectual Property? From IP to IPO What is Impact? From Atoms to Proteins Atoms and Molecules Atoms of Life Molecules of Life Proteins Genetics and DNA Sequencing DNA and the Genetic Code From DNA to Proteins and Cells History of Genetics Molecular Basis of Genetics DNA Sequencing and the Human Genome Project Sequencing Technologies Chemical Sequencing Sanger Sequencing, NGS and the $1,000 Genome Challenge Second Generation DNA Sequencing Third Generation DNA Sequencing Fourth Generation DNA Sequencing Sequencing Data Analysis Bioethics Business Aspects of Sequencing Technology and the Human Genome Project Post Human Genome Project: "Omics" Bio-Pharmaceutical R&D Stages of Bio-Pharmaceutical Drug Discovery and Clinical Development Stage 1: Drug Discovery Stage 2: Pre-Clinical Research Stages 3-4: Clinical Trials and FDA Review The Emerging Importance of "Biologics" Biomarkers and Stratified/Personalized Medicine The Past and Future of Bio-Pharmaceutical R&D Semiconductors: Progress through Collaboration Life Sciences Industry: Exclusive IP Deals and Limited Collaboration IMI and AMP Nanomedicine Computers in Nanomedicine Biocompatible Nanoparticles and Targeted Drug Delivery Dendrimers Liposomes Targeted Drug Delivery The Business of Nanotherapeutics Biomedical and Molecular Imaging Nanodiagnostics Regenerative Medicine: Stem Cells, Gene Therapy, Immunotherapy Impact of Nanomedicine The Gut Microbiome Central Nervous System: Brain and Spinal Cord Cancer and Immunology Cardiovascular Disease Diabetes Infectious Disease Tissue and Organ Transplantation The Healthcare Ecosystem AND BIOMEDICAL RESEARCH FUNDING It's all about the Patient/Consumer The Future of Funding for Basic Biomedical and Translational Research Public Health and Global Health Economics Global View of Healthcare Costs, Infant Mortality and Life Expectancy US Health Statistics Conclusions Acknowledgments References