Following an overview of nanotechnologies for diagnostic purposes, this book goes on to look at nanoparticle-based magnetic resonance, molecular and other imaging applications, as well as the potential roles of carbon nanotubes and bionanoparticles in biomedical applications. The book's main focus is on drug delivery systems based on nonporous and nanosize materials, solid lipid and polymeric nanoparticles, intelligent hydrogels, core-shell nanoparticles, and nanocapsules, rounded off by a discussion of their biomedical applications. The final part of this volume covers such biomedical strategies as gene therapy, synthetic gene-transfer vectors and targeted delivery.
Author(s): Challa S. S. R. Kumar
Edition: 1
Publisher: Wiley-VCH
Year: 2007
Language: English
Pages: 744
Tags: Специальные дисциплины;Наноматериалы и нанотехнологии;Нанобиотехнология;
Cover: Nanomaterials for Medical Diagnosis and Therapy......Page 1
Contents......Page 2
Preface......Page 14
1. Nanotechnologies for Diagnosis – Present and Future......Page 20
2. Superparamagnetic Nanoparticles of Iron Oxides for Magnetic Resonance Imaging Applications......Page 70
3. Carbon Nanotube-based Vectors for Delivering Immunotherapeutics and Drugs......Page 104
4. Core–Shell Nanoparticles for Drug Delivery and Molecular Imaging......Page 162
5. Nanotechnologies for Targeted Delivery of Drugs......Page 208
6. Nanoporous and Nanosize Materials for Drug Delivery Systems......Page 274
7. NANOEGG Technology for Drug Delivery......Page 329
8. Polymeric Nanomaterials – Synthesis, Functionalization and Applications in Diagnosis and Therapy......Page 361
9. Polymeric Nanoparticles for Drug Delivery......Page 428
10. Solid Lipid and Polymeric Nanoparticles for Drug Delivery......Page 490
11. Intelligent Hydrogels in Nanoscale Sensing and Drug Delivery Applications......Page 528
12. Nanoshells for Drug Delivery......Page 546
13. Bionanoparticles and their Biomedical Applications......Page 576
14. Nanotechnology for Gene Therapy – HVJ-E Vector......Page 616
15. Nanotoxicology of Synthetic Gene Transfer Vectors: Poly(ethyleneimine)- and Polyfectinmediated Membrane Damage and Apoptosis in Human Cell Lines......Page 648
16. Nanoparticles for the Treatment of Alzheimer’s Disease: Theoretical Rationale, Present Status and Future Perspectives......Page 663
Index......Page 726
