Nanobiosensors and Nanobioanalyses

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This book provides a comprehensive review of established, cutting-edge, and future trends in the exponentially growing field of nanomaterials and their applications in biosensors and bioanalyses. Part I focuses on the key principles and transduction approaches, reviewing the timeline featuring the important historical milestones in the development and application of nanomaterials in biosensors and bioanalyses. Part II reviews various architectures used in nanobiosensing designs focusing on nanowires, one- and two-dimensional nanostructures, and plasmonic nanobiosensors with interferometric reflectance imaging. Commonly used nanomaterials, functionalization of the nanomaterials, and development of nanobioelectronics are discussed in detail in Part III with examples from screen-printed electrodes, nanocarbon films, and semiconductor quantum dots. Part IV reviews the current applications of carbon nanotubes, nanoneedles, plasmonic sensors, electrochemical scanning microscopes, and field-effect transistors with the future outlook for emerging technologies. Attention is also given to potential challenges, in particular, of taking these technologies at the point-of-need. The book concludes by providing a condensed summary of the contents, with emphasis on future directions.

Nanomaterials have become an essential part of biosensors and bioanalyses in the detection and monitoring of medical, pharmaceutical, and environmental conditions, from cancer to chemical warfare agents. This book, with its distinguished editors and international team of expert contributors, will be an essential guide for all those involved in the research, design, development, and application of nanomaterials in biosensors and bioanalyses.

Author(s): Mun'delanji C. Vestergaard, Kagan Kerman, I-Ming Hsing, Eiichi Tamiya (eds.)
Edition: 1
Publisher: Springer Tokyo
Year: 2015

Language: English
Pages: 379
Tags: Biochemistry, general; Biotechnology; Biomedical Engineering; Nanochemistry

Front Matter....Pages i-xi
Front Matter....Pages 1-1
Nanobiosensors and Nanobioanalyses: A Review....Pages 3-20
Front Matter....Pages 21-21
Vertically Aligned Nanowire Array-Based Sensors and Their Catalytic Applications....Pages 23-40
Device Architecture and Biosensing Applications for Attractive One- and Two-Dimensional Nanostructures....Pages 41-70
Nanoimprinted Plasmonic Biosensors and Biochips....Pages 71-80
Nanoparticle Biosensing with Interferometric Reflectance Imaging....Pages 81-95
Front Matter....Pages 97-97
Nanomaterial-Based Dual Detection Platforms: Optics Meets Electrochemistry....Pages 99-120
Nanocarbon Film-Based Electrochemical Detectors and Biosensors....Pages 121-136
Hybrid Metallic Nanoparticles: Enhanced Bioanalysis and Biosensing via Carbon Nanotubes, Graphene, and Organic Conjugation....Pages 137-166
Novel Nanobiosensing Using a Focused Laser Beam....Pages 167-178
Semiconductor Quantum Dots and Energy Transfer for Optical Sensing and Bioanalysis: Principles....Pages 179-196
Semiconductor Quantum Dots and Energy Transfer for Optical Sensing and Bioanalysis: Applications....Pages 197-249
Nanoparticle-Based Detection of Protein Phosphorylation....Pages 251-267
Front Matter....Pages 269-269
Carbon Nanotubes: Advances, Integration and Applications to Printable Electrode-Based Biosensors....Pages 271-289
Specialized Nanoneedles for Intracellular Analysis....Pages 291-303
Plasmonic Sensors for Analysis of Proteins and an Oncologic Drug in Human Serum....Pages 305-333
Scanning Electrochemical Microscopy for Imaging Single Cells and Biomolecules....Pages 335-352
Field-Effect Transistors: Current Advances and Challenges in Bringing Them to Point-of-Care....Pages 353-371
Back Matter....Pages 373-379