Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered. Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.
Author(s): Jesse Kresak, Yuan (Frank) Shan M.D. (auth.), Domenico Coppola (eds.)
Series: Cancer Growth and Progression 16
Edition: 1
Publisher: Springer Netherlands
Year: 2014
Language: English
Pages: 601
Tags: Cancer Research; Pathology; Biomedicine general
Front Matter....Pages i-viii
Molecular Pathology and Diagnostics of Gliomas....Pages 1-17
Molecular Pathology and Diagnostics of Thyroid and Parathyroid Malignancies....Pages 19-55
Molecular Pathology and Diagnostics of Breast Cancer....Pages 57-73
Molecular Pathology and Diagnostics of Non-small Cell Lung Carcinoma....Pages 75-118
Molecular Pathology and Diagnostics of Colorectal Cancer....Pages 119-175
Molecular Pathology and Diagnostics in Esophago-gastric Cancer....Pages 177-210
Molecular-Genetic Testing in Hepatocellular Carcinoma and Its Premalignant Conditions....Pages 211-258
Molecular Diagnostics of Pancreatic Cancer....Pages 259-282
Molecular Pathology and Diagnostics of Prostate Cancer....Pages 283-327
Molecular Diagnosis of Bladder and Kidney Cancer....Pages 329-340
Molecular-Genetic Testing in Penile, Scrotal, and Testicular Cancer....Pages 341-364
Molecular Pathology and Diagnostics of Gynecologic Malignancies....Pages 365-395
Molecular Pathology of Bone and Soft Tissue Neoplasms and Potential Targets for Novel Therapy....Pages 397-421
Molecular Pathology and Diagnostics of Pancreatic Endocrine Neoplasms....Pages 423-448
Molecular Pathology and Diagnostics of Childhood Tumors....Pages 449-495
Molecular Pathology and Diagnostics of Cutaneous Malignancy....Pages 497-519
Molecular Diagnostics of Lymphoid Neoplasms....Pages 521-555
Molecular Diagnostics of Myeloid Neoplasms....Pages 557-587
Back Matter....Pages 589-601
