Review of previous edition: “I am often asked by physicists, mathematicians and engineers to recommend a book that would be useful to get them started in computational molecular biology. I am also often approached by my colleagues in computational biology to recommend a solid textbook for a graduate course in the area. Tamar Schlick has written the book that I will be recommending to both groups. Tamar has done an amazing job in writing a book that is both suitably accessible for beginners, and suitably rigorous for experts.” J. J. Collins, Boston University, USA. “Molecular modeling … is now an important branch of modern biochemistry. … Schlick has brought her unique interdisciplinary expertise to the subject. … One of the most distinguished characteristics of the book is that it makes the reading really fun … and the material accessible. … a crystal clear logical presentation … . Schlick has added a unique title to the collection of mathematical biology textbooks … . a valuable introduction to the field of computational molecular modeling. It is a unique textbook … .” Hong Qian, SIAM Review, 2005.
Author(s): Tamar Schlick (auth.)
Series: Interdisciplinary Applied Mathematics 21
Edition: 2
Publisher: Springer-Verlag New York
Year: 2010
Language: English
Pages: 723
Tags: Mathematical and Computational Biology;Biochemical Engineering;Simulation and Modeling;Biochemistry, general;Biophysics and Biological Physics
Front Matter....Pages i-xlv
Biomolecular Structure and Modeling: Historical Perspective....Pages 1-40
Biomolecular Structure and Modeling: Problem and Application Perspective....Pages 41-75
Protein Structure Introduction....Pages 77-104
Protein Structure Hierarchy....Pages 105-128
Nucleic Acids Structure Minitutorial....Pages 129-162
Topics in Nucleic Acids Structure: DNA Interactions and Folding....Pages 163-204
Topics in Nucleic Acids Structure: Noncanonical Helices and RNA Structure....Pages 205-236
Theoretical and Computational Approaches to Biomolecular Structure....Pages 237-264
Force Fields....Pages 265-298
Nonbonded Computations....Pages 299-344
Multivariate Minimization in Computational Chemistry....Pages 345-384
Monte Carlo Techniques....Pages 385-423
Molecular Dynamics: Basics....Pages 425-461
Molecular Dynamics: Further Topics....Pages 463-517
Similarity and Diversity in Chemical Design....Pages 519-553
Back Matter....Pages 555-723
