It has been 80 years since the subject of bacterial adhesion to surfaces was first brought forth, but only in the last two decades has the importance of this subject been recognized by medical microbiologists. The fact that bacterial attachment to the host tissue is a prerequisite for infection understandably led to the hope that infections could be prevented by blocking the adhesion of pathogenic bacteria. Progress in this field has been so rapid that it has become difficult to keep up with recent developments. This book contains the proceedings of the symposium on the Molecular Mechanisms of Microbial Adhesion, May 6-8, 1988. Both the symposium and this book were intended as an up-to-date review of the most recent findings concerning the adhesion of medically important bacteria. In addition, this book contains critical and provocative overviews of the past, present and future of this field.
Author(s): Edwin H. Beachey (auth.), Lech Switalski, Magnus Höök, Edwin Beachey (eds.)
Edition: 1
Publisher: Springer-Verlag New York
Year: 1989
Language: English
Pages: 226
Tags: Microbiology; Cell Biology; Pharmacology/Toxicology; Medical Microbiology; Internal Medicine
Front Matter....Pages i-xviii
Bacterial Adherence....Pages 1-4
Heterogeneity of Renal Glycoconjugates: Biochemical and Bacteriological Aspects....Pages 5-22
TCP Pilus Expression and Biogenesis by Classical and El Tor Biotypes of Vibrio Cholerae 01....Pages 23-35
Isolation of the Pre-Assembled Gal α(1–4)Gal-Specific Pilus-Associated Adhesin from the Periplasm in Uropathogenic Escherichia Coli....Pages 36-43
Interaction of Isogenic Pilus + and Pilus − Variants of Gonococci with a Human Epithelial Cell Line....Pages 44-51
Molecular Approaches to Characterization of Mycoplasmal Adhesins....Pages 52-76
Current Experience from the Interaction of Bacteria with Glycosphingolipids....Pages 77-96
Molecular Basis for Fibronectin-Mediated Adherence in the Syphilis Spirochetes....Pages 97-106
A Fibronectin Binding Protein from Staphylococcus Aureus and its Role in Bacterial Adherence....Pages 107-117
Evolutionary Conservation of the Binding Site of a Laminin Receptor as Determined by Monoclonal Antibodies and Hydropathically Complementary Peptides....Pages 118-127
Effect of Mucosal Antibodies to M Protein on Colonization by Group A Streptococci....Pages 128-142
Adsorbed Salivary Proline-Rich Proteins as Bacterial Receptors on Apatitic Surfaces....Pages 143-163
Bacterial and Host Cell Receptors for the Actinomyces spp. Fimbrial Lectin....Pages 164-170
Adhesins of Bacteroides Loescheii....Pages 171-176
The Race for the Surface: Microbes, Tissue Cells, and Biomaterials....Pages 177-211
Bacterial Adherence as Target for Preventing Infection....Pages 212-221
Back Matter....Pages 223-226
