Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders
Author(s): Akhlaq A. Farooqui
Publisher: Academic Press
Year: 2020
Language: English
Pages: 400
City: London
Front-Ma_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and-R
Front matter
Copyri_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and-Reg
Copyright
Dedicat_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and-Re
Dedication
About-the-_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and
About the author
Prefa_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and-Rege
Preface
Acknowledg_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and
Acknowledgments
List-of-abbre_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--
List of abbreviations
Chapter-1---Molecular-aspects-of-ne_2021_Molecular-Aspects-of-Neurodegenerat
Molecular aspects of neurodegeneration and classification of neurological disorders
Introduction
Molecular aspects of neurodegeneration
Biomarkers for acute neurodegeneration
Biomarkers for chronic neurodegeneration
Neurodegenerative diseases
Molecular aspects of Alzheimer’s disease
Molecular aspects of Huntington’s disease
Molecular aspects of Parkinson’s disease
Molecular aspects of amyotrophic lateral sclerosis
Molecular aspects of prion diseases
Neuropsychiatric diseases
Molecular aspects of depression
Molecular aspects of autism
Conclusion
References
Chapter-2---Effect-of-diet-on-neur_2021_Molecular-Aspects-of-Neurodegenerati
Effect of diet on neurological disorders and regenerative processes in the brain
Introduction
Effects of Western diet on neurological disorders
Effects of Mediterranean diet on neurological disorders
Effects of Okinawan diet on neurological disorders
Effects of vegetarian diet on neurological disorders
Effects of ketogenic diet on neurological disorders
Effects of ketogenic diet on gut microbiota
Effects of diet on regeneration
Conclusion
References
Chapter-3---Molecular-mechanisms_2021_Molecular-Aspects-of-Neurodegeneration
Molecular mechanisms of neurodegeneration in neurotraumatic diseases
Introduction
Neurochemical aspects of neurotraumatic injuries
Neurochemical aspects of stroke
Neurochemical aspects of hemorrhagic stroke
Neurochemical aspects of ischemic stroke
Contribution of gut microbiota in poststroke brain injury
Neurochemical aspects of traumatic brain injury
Contribution of gut microbiota in traumatic brain injury-mediated neurodegeneration
Neurochemical aspects of spinal cord injury
Contribution of gut microbiota in spinal cord injury
Neurochemical aspects of chronic traumatic encephalopathy
Contribution of gut microbiota in CTE
Risk factors and biochemical markers for CTE
Conclusion
References
Chapter-4---Molecular-mechanisms_2021_Molecular-Aspects-of-Neurodegeneration
Molecular mechanisms of neurodegeneration in neurodegenerative diseases
Introduction
Molecular mechanisms contributing to neurodegeneration in Alzheimer’s disease
Contribution of microbiota in the pathogenesis of Alzheimer’s disease
Molecular mechanisms contributing to neurodegeneration in Parkinson’s disease
Contribution of gut microbiota in the pathogenesis of Parkinson’s disease
Molecular mechanisms contributing to neurodegeneration in amyotrophic sclerosis
Contribution of gut microbiota in the pathogenesis of amyotrophic lateral sclerosis
Molecular mechanisms contributing to neurodegeneration in Huntington’s disease
Contribution of gut microbiota in Huntington’s disease
Conclusion
References
Chapter-5---Molecular-mechanisms_2021_Molecular-Aspects-of-Neurodegeneration
Molecular mechanisms of neurodegeneration in neuropsychiatric diseases
Introduction
Gut dysbiosis and neuropsychiatric diseases
Molecular mechanisms contributing to neurodegeneration in depression
Contribution of microbiota in the pathogenesis of depression
Molecular aspects of autism spectrum disorders
Contribution of microbiota in the pathogenesis of ASDs
Molecular aspects of bipolar disorders
Contribution of microbiota in the pathogenesis of bipolar disorders
Molecular aspects of schizophrenia
Contribution of microbiota in the pathogenesis of schizophrenia
Molecular aspects of attention-deficit/hyperactivity disorder
Contribution of microbiota in the pathogenesis of attention-deficit/hyperactivity disorder
Conclusion
References
Chapter-6---Molecular-aspects-of-r_2021_Molecular-Aspects-of-Neurodegenerati
Molecular aspects of regeneration and neuroprotection in neurotraumatic diseases
Introduction
Recovery from stroke-mediated neuronal injury
Intrinsic mechanisms contributing to poststroke recovery
Neuroprotective agents promoting poststroke recovery
Recovery from traumatic brain injury-mediated neuronal injury
Neuroprotective agents for promoting post-TBI recovery
Recovery from spinal cord injury-mediated neuronal injury
Neuroprotective agents promoting neurogenesis and recovery in spinal cord injury
Conclusion
References
Chapter-7---Molecular-aspects-of-re_2021_Molecular-Aspects-of-Neurodegenerat
Molecular aspects of regeneration and neuroprotection in neurodegenerative diseases
Introduction
Factors influencing adult neurogenesis
Levels of BDNF in Alzheimer’s disease
Levels of BDNF in Parkinson’s disease
Neurogenesis in Parkinson’s disease
Levels of growth factors in Huntington’s disease
Adult neurogenesis in brains from Huntington’s disease
Levels of BDNF in amyotrophic lateral sclerosis
Adult neurogenesis in brain from amyotrophic lateral sclerosis
Conclusion
References
Chapter-8---Molecular-aspects-of-re_2021_Molecular-Aspects-of-Neurodegenerat
Molecular aspects of regeneration and neuroprotection in neuropsychiatric diseases
Introduction
Neurogenesis in adult brain
Neurobiological significance of adult neurogenesis
BDNF and adult neurogenesis in neuropsychiatric disorders
Crosstalk among BDNF, glucocorticoids, and neurogenesis
Neurochemical aspects of depression
BDNF and depression
Involvement of BDNF and neurogenesis in depression
Involvement of BDNF in autism
Involvement of neurochemical changes in anxiety
Adult neurogenesis in anxiety
BDNF and neurogenesis in bipolar disorder
BDNF, neurogenesis, and schizophrenia
BDNF, PTSD, and neurogenesis
Pharmacological and nonpharmacological treatments of neuropsychiatric diseases
Nonpharmacological treatment of neuropsychiatric diseases
Conclusion
References
Chapter-9---Strategies-for-the-potenti_2021_Molecular-Aspects-of-Neurodegene
Strategies for the potential treatment of neurological disorders with Chinese and Indian medicinal plants
Introduction
Chinese medicinal plants
Neurochemical effects of huperzine
Huperzine in ischemic injury
Huperzine in traumatic brain and spinal cord injuries
Huperzine in neurodegenerative diseases
Huperzine in Alzheimer’s disease
Huperzine in depression and schizophrenia
Neurochemical effects of Ginkgo biloba
Ginkgo biloba and ischemic injury
Ginkgo biloba and Alzheimer’s disease
Ginkgo biloba and neuropsychiatric diseases
Neurochemical effects of radix ginseng
Radix ginseng and ischemia
Radix ginseng and Alzheimer’s disease
Radix ginseng and Parkinson’s disease
Radix ginseng and Huntington’s disease
Radix ginseng and depression
Neurochemical effects of green tea
Green tea and ischemic injury
Green tea and Alzheimer’s disease
Green tea and Parkinson’s disease
Green tea and neuropsychiatric diseases
Indian medicinal plants
Neurochemical effects of Ashwagandha
Ashwagandha and ischemic injury
Ashwagandha in traumatic brain injury
Ashwagandha in Alzheimer’s disease
Ashwagandha and Parkinson’s disease
Ashwagandha in depression and posttraumatic stress disorder
Neurochemical effects of curcumin
Curcumin in ischemic injury
Curcumin and traumatic brain injury
Curcumin and spinal cord injury
Curcumin and Alzheimer’s disease
Curcumin and depression
Neurochemical effects of brahmi (Bacopa monnieri)
Bacopa monnieri and ischemia
Bacopa monnieri and Alzheimer’s disease
Bacopa monnieri and Parkinson’s disease
Bacopa monnieri and depression
Conclusion
References
Chapter-10---Summery--perspective--and_2021_Molecular-Aspects-of-Neurodegene
Summery, perspective, and future studies on neurodegeneration and regeneration in neurological disorders
Introduction
Effect of diet on neurodegeneration and regeneration
Effects of exercise on neurodegeneration and regeneration in neurological disorders
Balance between neurodegeneration and regeneration in neurodegenerative diseases
Future studies on neurodegeneration and regeneration in neurological disorders
Conclusion
References
Inde_2021_Molecular-Aspects-of-Neurodegeneration--Neuroprotection--and-Regen
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