The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling.
- Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed.
- Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates
Author(s): Pan, J
Series: Woodhead Publishing Series in Biomaterials
Edition: 1
Publisher: Woodhead Pub Ltd, , Elsevier Ltd
Year: 2015
Language: English
Pages: 249
Tags: Химия и химическая промышленность;Высокомолекулярные соединения;
Content:
Front matter, Pages i-iii
Copyright, Page iv
List of contributors, Page ix, X. Chen, A. Gleadall, X. Han, J. Pan
Woodhead Publishing Series in Biomaterials, Pages xi-xv
1 - Introduction to computer modelling for the design of biodegradable medical devices, Pages 3-13
2 - Modelling degradation of amorphous biodegradable polyesters: basic model, Pages 15-31, J. Pan, X. Chen
3 - Modelling degradation of amorphous biodegradable polyesters: advanced model, Pages 33-51, J. Pan, X. Chen
4 - Modelling degradation of semi-crystalline biodegradable polyesters, Pages 53-69
5 - Modelling biodegradation of composite materials made of biodegradable polyesters and tricalcium phosphates (TCPs), Pages 71-87
6 - Modelling heterogeneous degradation of polymeric devices due to short chain diffusion, Pages 89-109, J. Pan, X. Chen
7 - Finite element analysis (FEA) of biodegradation of polymeric medical devices, Pages 113-130,131e-138e,131-140, X. Han
8 - The effective diffusion coefficient of degrading polymers, Pages 141-161, X. Han
9 - Mechanical properties of biodegradable polymers for medical applications, Pages 163-199, A. Gleadall
10 - Molecular and multi-scale modelling methods of polymer device degradation, Pages 201-231, X. Han
Index, Pages 233-244
