Microscale Technologies for Cell Engineering

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This book offers readers cutting-edge research at the interface of polymer science and engineering, biomedical engineering, materials science, and biology. State-of-the-art developments in microscale technologies for cell engineering applications are covered, including technologies relevant to both pluripotent and adult stem cells, the immune system, and somatic cells of the animal and human origin.

This book bridges the gap in the understanding of engineering biology at multiple length scale, including microenvironmental control, bioprocessing, and tissue engineering in the areas of cardiac, cartilage, skeletal, and vascular tissues, among others. This book also discusses unique, emerging areas of micropatterning and three-dimensional printing models of cellular engineering, and contributes to the better understanding of the role of biophysical factors in determining the cell fate. Microscale Technologies for Cell Engineering is valuable for bioengineers, biomaterial scientists, tissue engineers, clinicians, immunoengineers, immunologists and stem cell biologists, as it offers a review of the current cutting-edge cell engineering research at multiple length scale and will be valuable in developing new strategies for efficient scale-up and clinical translation.

Author(s): Ankur Singh, Akhilesh K. Gaharwar
Publisher: Springer
Year: 2015

Language: English
Pages: viii+330
Tags: Nanotechnology and Microengineering; Biomedical Engineering; Stem Cells

Front Matter....Pages i-viii
Front Matter....Pages 1-1
Microscale Technologies for Engineering Complex Tissue Structures....Pages 3-25
Photochemical Patterning of Cellular Microenvironments....Pages 27-46
Microfabrication of Patterned Co-cultures for Controllable Cell–Cell Interfaces....Pages 47-67
3D Bioprinting Technologies for Cellular Engineering....Pages 69-89
Front Matter....Pages 91-91
Engineered Stem Cell-Based Scaffolds and Patches for Heart Disorders....Pages 93-112
Stem Cell and Stem Cell-Derived Molecular Therapies to Enhance Dermal Wound Healing....Pages 113-141
Spatial Patterning of Stem Cells to Engineer Microvascular Networks....Pages 143-166
Microscale Approaches for Molecular Regulation of Skeletal Development....Pages 167-193
Front Matter....Pages 195-195
Microfluidic Platforms for the Interrogation of Intravascular Cellular Trafficking Mechanisms Influenced by Hemodynamic Forces....Pages 197-218
Microscale Technologies for High-Throughput Analysis of Immune Cells....Pages 219-230
Microscale Cell Encapsulation Materials and Fabrication Techniques for Type 1 Diabetes....Pages 231-248
Engineering Mechanical, Biochemical, and Topographical Niche Cues by Photocrosslinkable, Microribbon-Like Hydrogels....Pages 249-266
Front Matter....Pages 267-267
Nano- and Microscale Delivery Systems for Cardiovascular Therapy....Pages 269-289
Nanoparticulate Systems for Controlling Monocyte/Macrophage Behavior....Pages 291-304
Drug-Eluting Nanotubes for Cellular Bioactivity....Pages 305-318
Back Matter....Pages 319-330