Metal Ions in Biological Systems: Volume 14: Inorganic Drugs in Deficiency and Disease

Cover
Half Title
Title Page
Copyright Page
Preface to The Series
Preface to Volume 14
Table of Contents
List of Contributors
Contents of Other Volumes
Chapter 1. Drug-Metal Ion Interaction in the Gut
1. Introduction
2. In Vitro Models of Drug Absorption Interactions
3. Interactions With Metal-Contatning Antacids or Metal Salts
4. Implications of Absorption Interactions on Drug Pharmacokinetic Profiles
5. Clinical Significance of Drug Absorption Interactions with Metal Ions and Metal-containing Antacids
References
Chapter 2. Zinc Deficiency and its Therapy
1. History
2. Causes of Human Zinc Deficiency
3. Clinical Manifestations of Zinc Deficiency
4. Laboratory Diagnosis of Zinc Deficiency
5. Treatment of Human Zinc Deficiency
Acknowledgments
References
Chapter 3. The Pharmacological use of Zinc
1. History
2. Zinc Absorption
3. Oral Regimens
4. Diseases Which May Respond to Zinc Therapy
5. Mechanism of Action
6. Toxicity
7. The Future
Acknowledgments
References
Chapter 4. The Anti-Inflammatory Activities of Copper Complexes
1. Introduction
2. Normal Physiology of Copper Complexes
3. Altered Physiology of Copper Complexes in Disease with Inflammatory Components
4. Pharmacologic Activities of Copper Complexes
5. Clinical Effectiveness of Copper Complexes in the Treatment of Rheumatoid and other Degenerative Diseases
6. Biochemistry of the Anti-Inflammatory Copper Complexes: Possible Mechanisms of Action
7. Chemistry of Copper Complexes
Acknowledgments
References
Chapter 5. Iron-Containing Drugs
1. Introduction to the Chemistry of Iron
2. Biochemistry of Iron
3. Diseases Basho on Iron
4. Iron Therapy
Glossary of Medical Terms
References
Chapter 6. Gold Complexes as Metallo-Drugs
1. Introduction
2. Gold Drugs Against Arthritis
3. Gold Poisoning, Contraindications, and Treatment
4. Gold Metabolism (Absorption, Distribution, and Excretion)
5. Physical Methods for Determining Interaction of Gold Drugs in Biological Systems
6. Detection and Estimation of Gold in Biological Systems
References
Chapter 7. Metal Ions and Chelating Agents in Antiviral Chemotherapy
1. Introduction
2. The Viral Cycle and its Impact on Host Organisms
3. Interfering With the Viral Cycle
4. Chelation and Biological Activity
5. Chelatinc agents with Antiviral Activity
6. Delivery of Drugs to Targets
7. Metal Ions in Antiviral Chemotherapy
Abbreviations
References
Chapter 8. Complexes of Hallucinogenic Drugs
1. Introduction
2. The Chemistry of Hallucinogenic Drugs
3. The Role of Metal Ions in the Actions of Drugs
4. Complexes of Hallucinogenic and Related Drugs
5. Conclusions
Abbreviations
References
Chapter 9. Lithium in Psychiatry
1. Introduction
2. Lithium in Psychiatry
3. Chemical Aspects of Lithium
4. Pharmacological and Biochemical Aspects of Lithium
5. Conclusions
References
Author Index
Subject Index