The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
Author(s): W. James Nelson (Eds.)
Series: Current Topics in Membranes 43
Edition: 1st
Publisher: Elsevier, Academic Press
Year: 1996
Language: English
Pages: ii-xx, 1-427
Content:
Series Editors
Page ii
Edited by
Page iii
Copyright page
Page iv
Contributors
Pages xiii-xv
Preface
Pages xvii-xviii
W.J. Nelson
Previous Volumes in Series
Pages xix-xx
Chapter 1 Getting There Is Only Half the Fun Original Research Article
Pages 1-13
Michael Edidin
Chapter 2 Once There, Making the Descision To Stay or Leave Original Research Article
Pages 15-25
Kenneth A. Beck, W. James Nelson
Chapter 3 Interactions between Microtubules and Intracellular Membranes: The Roles of Microtubule-Based Motors and Accessory Proteins Original Research Article
Pages 27-52
Trina A. Schroer, Steven R. Gill
Chapter 4 Role of the Cytoskeleton and Molecular Motors in Transport between the Golgi Complex and Plasma Membrane Original Research Article
Pages 53-71
Karl R. Fath, David R. Burgess
Chapter 5 Membrane-Cytoskeleton Interaction in Regulated Exocytosis and Apical Insertion of Vesicles in Epithelial Cells Original Research Article
Pages 73-96
Xuebiao Yao, John G. Forte
Chapter 6 The Spectrin Cytoskeleton and Organization of Polarized Epithelial Cell Membranes Original Research Article
Pages 97-128
Prasad Devarajan, Jon S. Morrow
Chapter 7 Axonal Ankyrins and Ankyrin-Binding Proteins: Potential Participants in Lateral Membrane Domains and Transcellular Connections at the Node of Ranvier Original Research Article
Pages 129-145
Stephen Lambert, Vann Bennett
Chapter 8 Molecular and Genetic Dissection of the Membrane Skeleton in Drosophila Original Research Article
Pages 147-167
Ronald R. Dubreuil
Chapter 9 Membrane–Cytoslteleton Interactions with Cadherin Cell Adhesion Proteins: Roles of Catenins as Linker Proteins Original Research Article
Pages 169-185
Margaret J. Wheelock, Karen A. Knudsen, Keith R. Johnson
Chapter 10 The Desmosome: A Component System for Adhesion and Intermediate Filament Attachment Original Research Article
Pages 187-209
Andrew P. Kowalczyk, Kathleen J. Green
Chapter 11 Protein Interactions in the Tight Junction: The Role of MAGUK Proteins in Regulating Tight Junction Organization and Function Original Research Article
Pages 211-235
Alan S. Fanning, Lynne A. Lapierre, Alexandra R. Brecher, Christina M. Van Itallie, James Melvin Anderson
Chapter 12 Regulation of Membrane Protein Organization at the Neuromuscular Junction Original Research Article
Pages 237-263
Gregory G. Gayer, James T. Campanelli, Richard H. Scheller
Chapter 13 Integrin Signaling and the Platelet Cytoskeleton Original Research Article
Pages 265-291
Martin Eigenthaler, Sanford J. Shattil
Chapter 14 Interactions between the Membrane-Cytoskeleton and CD44 during Lymphocyte Signal Transduction and Cell Adhesion Original Research Article
Pages 293-312
Lilly Y.W. Bourguignon
Chapter 15 Dynamic Properties of the Lymphocyte Membrane-Cytoskeleton: Relationship to Lymphocyte Activation Status, Signal Transduction, and Protein Kinase C Original Research Article
Pages 313-343
Elizabeth A. Repasky, Jennifer D. Black
Chapter 16 Regulation of Epithelial Ion Channel Activity by the Membrane-Cytoskeleton Original Research Article
Pages 345-372
Peter R. Smith, Dale J. Benos
Chapter 17 Role of Actin Filament Organization in Ion Channel Activity and Cell Volume Regulation Original Research Article
Pages 373-396
Horacio F. Cantiello, Adriana G. Prat
Chapter 18 Role of the Cytoskeleton in Membrane Alterations in Ischemic or Anoxic Renal Epithelia Original Research Article
Pages 397-421
R. Brian Doctor, Robert Bacallao, Lazaro J. Mandel
Index
Pages 423-427
