Maintaining the high standard of quality that made previous editions so successful, this totally revised and updated text incorporates the most recent advances in basic and clinical immunology-emphasizing diagnostic and clinical applications as well as state-of-the-art discussions of the principles and strategies for modulation of the immune response and treatment of hypersensitivity, autoimmune, and immune deficiency diseases. Includes clinical case studies as well as end-of-chapter questions-in the USML multiple choice format-for self-evaluation and preparation for licensure and specialty boards! Continuing as the only textbook providing a balanced discussion of basic and clinical immunology, the Fifth Edition of Medical Immunology offers ·a current review of the basic principles that govern the immune response ·an updated review of phagocytic cell physiology and functional deficiencies ·a new comprehensive section on diagnostic immunology ·extensively revised and updated discussions on tolerance, autoimmunity, and hypersensitivity diseases ·state-of-the-art discussion of immunosuppression and immunomodulation ·a modern overview of cancer immunology ·current discussions on the diagnosis, pathogenesis, and management of primary and secondary immune deficiency diseases ·and more! Written by seasoned experts in the field, the Fifth Edition of Medical Immunology is an exceptional text for advanced undergraduate and graduate students taking courses in immunology in departments of medicine, dentistry, and veterinary science; medical fellows, residents, and interns; and practicing physicians taking seminars in clinical immunology.
Author(s): Gabriel Virella
Edition: 5
Year: 2001
Language: English
Pages: 668
Tags: Медицинские дисциплины;Иммунология и аллергология;
Preface......Page 4
Contents......Page 6
Contributors......Page 10
Introduction......Page 12
Cells and Tissues Involved in the Immune Response......Page 22
Major Histocompatibility Complex......Page 42
The Induction of an Immune Response: Antigens, Lymphocytes, and Accessory Cells......Page 62
Immunoglobulin Structure......Page 86
Biosynthesis, Metabolism, and Biological Properties of Immunoglobulins......Page 104
Genetics of Immunoglobulins......Page 116
Antigen-Antibody Reactions......Page 130
The Complement System......Page 146
Lymphocyte Ontogeny and Membrane Markers......Page 172
Cell-Mediated Immunity......Page 204
The Humoral Immune Response and Its Induction by Active Immunization......Page 236
Phagocytic Cells......Page 256
Infections and Immunity......Page 270
Diagnostic Immunology......Page 288
Tolerance and Autoimmunity......Page 322
Organ-Specific Autoimmune Diseases......Page 352
Systemic Lupus Erythematosus......Page 370
Rheumatoid Arthritis......Page 388
Hypersensitivity Reactions......Page 406
IgE-Mediated (Immediate) Hypersensitivity......Page 422
Immunohematology......Page 440
Immune Complex Diseases......Page 462
Immune System Modulators......Page 484
Transplantation Immunology......Page 510
Tumor Immunology......Page 528
Malignancies of the Immune System......Page 540
Diagnosis of Immunodeficiency Diseases......Page 566
Primary Immunodeficiency Diseases......Page 584
AIDS and Other Acquired Immunodeficiency Diseases......Page 608
Index......Page 642
