This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric GfÑfnfnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.
Author(s): Stephen R. Sprang (Eds.)
Series: Advances in Protein Chemistry 74
Edition: 1
Publisher: Academic Press
Year: 2007
Language: English
Pages: 1-253
Content:
Structural Basis of Effector Regulation and Signal Termination in Heterotrimeric Gα Proteins Review Article
Pages 1-65
Stephen R. Sprang, Zhe Chen, Xinlin Du
How do Receptors Activate G Proteins? Review Article
Pages 67-93
William M. Oldham, Heidi E. Hamm
Some Mechanistic Insights into GPCR Activation from Detergent‐Solubilized Ternary Complexes on Beads Review Article
Pages 95-135
Tione Buranda, Anna Waller, Yang Wu, Peter C. Simons, Sean Biggs, Eric R. Prossnitz, Larry A. Sklar
Activation of G Protein–Coupled Receptors Review Article
Pages 137-166
Xavier Deupi, Brian Kobilka
Kinetic Analysis of G Protein–Coupled Receptor Signaling Using Fluorescence Resonance Energy Transfer in Living Cells Review Article
Pages 167-188
Martin J. Lohse, Carsten Hoffmann, Viacheslav O. Nikolaev, Jean‐Pierre Vilardaga, Moritz BÜnemann
Regulation of Rho Guanine Nucleotide Exchange Factors by G Proteins Review Article
Pages 189-228
Paul C. Sternweis, Angela M. Carter, Zhe Chen, Shahab M. Danesh, Ying‐Fan Hsiung, William D. Singer
Author Index
Pages 229-246
Subject Index
Pages 247-253
Preface
Pages VII-X
Stephen Sprang
Contents
Pages V-VI
