Mathematical Aspects of Pattern Formation in Biological Systems

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This monograph is concerned with the mathematical analysis of patterns which are encountered in biological systems. It summarises, expands and relates results obtained in the field during the last fifteen years. It also links the results to biological applications and highlights their relevance to phenomena in nature. Of particular concern are large-amplitude patterns far from equilibrium in biologically relevant models.

The approach adopted in the monograph is based on the following paradigms:

• Examine the existence of spiky steady states in reaction-diffusion systems and select as observable patterns only the stable ones

• Begin by exploring spatially homogeneous two-component activator-inhibitor systems in one or two space dimensions

• Extend the studies by considering extra effects or related systems, each motivated by their specific roles in developmental biology, such as spatial inhomogeneities, large reaction rates, altered boundary conditions, saturation terms, convection, many-component systems.

Mathematical Aspects of PatternFormation in Biological Systems will be of interest to graduate students and researchers who are active in reaction-diffusion systems, pattern formation and mathematical biology.

Author(s): Juncheng Wei, Matthias Winter (auth.)
Series: Applied Mathematical Sciences 189
Edition: 1
Publisher: Springer-Verlag London
Year: 2014

Language: English
Pages: 319
Tags: Partial Differential Equations; Mathematical and Computational Biology; Genetics and Population Dynamics; Physiological, Cellular and Medical Topics

Front Matter....Pages I-XII
Introduction....Pages 1-12
Existence of Spikes for the Gierer-Meinhardt System in One Dimension....Pages 13-39
The Nonlocal Eigenvalue Problem (NLEP)....Pages 41-70
Stability of Spikes for the Gierer-Meinhardt System in One Dimension....Pages 71-89
Existence of Spikes for the Shadow Gierer-Meinhardt System....Pages 91-106
Existence and Stability of Spikes for the Gierer-Meinhardt System in Two Dimensions....Pages 107-148
The Gierer-Meinhardt System with Inhomogeneous Coefficients....Pages 149-173
Other Aspects of the Gierer-Meinhardt System....Pages 175-247
The Gierer-Meinhardt System with Saturation....Pages 249-261
Spikes for Other Two-Component Reaction-Diffusion Systems....Pages 263-270
Reaction-Diffusion Systems with Many Components....Pages 271-286
Biological Applications....Pages 287-295
Appendix....Pages 297-304
Back Matter....Pages 305-319