Ideal for all health care professionals who evaluate, diagnose, treat, or refer patients with endocrine disease or disorders, Manual of Endocrinology and Metabolism, Fifth Edition, brings together nearly 150 global authorities who share their knowledge and expertise on endocrine disorders in children, adolescents, and adults. Using a concise outline format, this thoroughly updated manual presents clinical information and protocols needed in everyday practice, with an emphasis on diagnosis and treatment. Succinct chapters and an abundance of tables and diagrams make complex information easy to find and understand.
Includes coverage of fundamental understandings and treatment modalities as well as recent therapies, new methods of treatment, new understandings of endocrine physiology, and new surgical approaches to disease states
Covers evaluation, pathophysiology, management, and treatment at every age of life, along with short- and long-term goals of reversibility and prevention
New chapters include transgender medicine, flushing and sweating, nasal administration of hormones, the growth plate, as well as traumatic brain injury and hypopituitarism
New topics include galactorrhea; preoperative, intraoperative, and postoperative management following pituitary surgery; growth hormone in adults, polycystic ovary syndrome, hypercalcemic crisis, parathyroid hormone-related protein, congenital hyperinsulinism, and hypokalemic periodic and non-periodic paralysis
New and expanded coverage of diabetes mellitus includes hypoglycemia-associated autonomic failure, glucocorticoid-induced hyperglycemia, C-peptide, cystic fibrosis-related diabetes, the artificial pancreas, glycated proteins, inhaled insulin, and the application of stem cells in diabetes mellitus
Serves as an excellent resource for board preparation, as well as a concise daily reference for endocrinologists, general practitioners, internists, pediatricians, physician assistants, nurse practitioners, and others who see patients with primary or underlying endocrine disease
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Author(s): Norman Lavin MD, PhD
Series: Lippincott Manual Series
Edition: 5th Edition
Publisher: Wolters Kluwer Health
Year: 2018
Language: English
Commentary: CONVERTED PDF
Pages: 2040
Title Page......Page 3
Copyright......Page 4
Contents......Page 12
A Brief Autobiography......Page 6
Preface......Page 7
Dedication......Page 9
Acknowledgments......Page 11
1 Clinical Molecular Endocrinology Laboratory Testing......Page 40
2 Hormone-Resistant States......Page 57
3 Genetics of Endocrinology......Page 89
4 The Growth Plate......Page 113
5 Anterior Pituitary Diseases......Page 131
6 Hypopituitarism after Traumatic Brain Injury......Page 158
7 Prolactin......Page 169
8 Nipple Discharge/Galactorrhea......Page 182
9 Acromegaly/Gigantism......Page 196
10 Clinical Disorders of Vasopressin......Page 207
11 Preoperative, Intraoperative, and Postoperative Management Following Pituitary Surgery......Page 231
12 Growth Hormone in Adults......Page 252
13 Pituitary Disorders and Tall Stature in Children......Page 277
14 Short Stature and Growth Hormone Therapy......Page 313
15 Laron Syndrome......Page 343
16 Prader–Willi Syndrome......Page 348
17 The Adrenal Cortex and Mineralocorticoid Hypertension......Page 357
18 Pheochromocytoma and Paraganglioma......Page 417
19 Hormonal Hypertension......Page 431
20 Use of Salivary Cortisol Assay to Screen for Cushing Syndrome/Disease......Page 456
21 Adrenal Hormones during Acute and Chronic Illness: Evaluation and Treatment......Page 464
22 Congenital Adrenal Hyperplasia......Page 476
23 Adrenal Steroid Excess in Childhood......Page 496
24 Adrenal Insufficiency in Childhood......Page 510
25 Female Reproductive Endocrinology in Adults......Page 523
26 Polycystic Ovary Syndrome......Page 547
27 Male Reproductive Disorders in Adults......Page 556
28 Disorders of Sexual Development in the Pediatric and Adolescent Male......Page 611
29 Early, Precocious, and Delayed Female Pubertal Development......Page 649
30 Ambiguous Genitalia......Page 681
31 Disorders of Calciotropic Hormones in Adults......Page 699
32 Hypercalcemic Crisis......Page 753
33 Metabolic Bone Disease......Page 764
34 Parathyroid Hormone-Related Protein......Page 802
35 Common Bone and Mineral Disorders of Childhood......Page 811
36 Evaluation of Thyroid Function......Page 873
37 Thyroiditis......Page 894
38 Hypothyroidism and Hyperthyroidism......Page 910
39 Thyroid Tumors in Adults......Page 935
40 Newborn Thyroid Disorders and Screening......Page 948
41 Thyroid Nodules and Thyroid Cancer in Children and Adolescents......Page 976
42 Thyroid Disorders in Children and Adolescents......Page 996
43 Obesity......Page 1046
44 Disorders of Lipid Metabolism......Page 1067
45 Hypoglycemia in Adults......Page 1093
46 Hypoglycemia in Infants and Children......Page 1126
47 Congenital Hyperinsulinism......Page 1152
48 Introduction to Inborn Errors of Metabolism......Page 1167
49 Glycogen Storage Diseases......Page 1183
50 Hypokalemic Paralysis......Page 1206
51 Etiology, Pathogenesis, and Therapy of Type 1 Diabetes Mellitus......Page 1224
52 Diagnosis and Management of Type 1 Diabetes Mellitus in Children, Adolescents and Young Adults......Page 1245
53 Hypoglycemia-Associated Autonomic Failure (HAAF) in Diabetes Mellitus......Page 1280
54 Diabetic Ketoacidosis......Page 1282
55 Type 2 Diabetes Mellitus......Page 1314
56 Glucose Control in Glucocorticoid-Induced Hyperglycemia......Page 1343
57 Bariatric Surgery in Adults with Type 2 Diabetes......Page 1346
58 Diabetes Mellitus and the Geriatric Patient......Page 1355
59 Diabetes Mellitus Type 2, Obesity, Dyslipidemia, and the Metabolic Syndrome in Children......Page 1378
60 Type 1.5 Diabetes: Overlay between Type 1 and Type 2 Diabetes......Page 1422
61 C-Peptide......Page 1427
62 Cystic Fibrosis Related Diabetes......Page 1434
63 Diabetes in Pregnancy......Page 1451
64 Management of Diabetes Mellitus in the Perioperative Period......Page 1467
65 Diabetes Mellitus: Recent Developments and Clinical Implications......Page 1479
66 Artificial Pancreas......Page 1503
67 Glycated Proteins in the Diagnosis and Management of Type I and Type II Diabetes Mellitus......Page 1513
68 Inhaled Insulin......Page 1519
69 The Application of Stem Cells in Diabetes Mellitus......Page 1530
70 The Care of Gender-nonconforming and Transgender Youth......Page 1537
71 Hormone Therapy in Transgender Adults......Page 1548
72 How to Manage Men with Low Testosterone......Page 1560
73 The Use of Hormones in Female Sexual Dysfunction......Page 1573
74 Menopausal Hormone Therapy......Page 1588
75 Endocrine Diseases in Pregnancy......Page 1597
76 Fetal Endocrinology and Neonatal Emergencies......Page 1640
77 Hormones and Aging......Page 1658
78 Neuroendocrine (APUD) Syndromes......Page 1678
79 Multiple Endocrine Neoplasia Syndromes......Page 1697
80 Radiology, Nuclear Medicine, and Endocrinology......Page 1705
81 Surgery for Endocrine Disorders......Page 1717
82 Surgical Management of Pediatric Endocrine Diseases......Page 1740
83 Biomarkers Used in the Screening, Diagnosis, Management, and Surveillance of Endocrine Cancers......Page 1762
84 Autoimmune Endocrine Syndromes......Page 1775
85 Management of Some Hormone-Dependent Cancers with Analogs of Hypothalamic Hormones......Page 1783
86 Endocrine-Disrupting Chemicals......Page 1799
87 Flushing and Sweating......Page 1807
88 Intranasal Hormones......Page 1815
89 The Female Athlete......Page 1826
Appendix A Protocols for Stimulation and Suppression Tests Commonly Used in Clinical Endocrinology......Page 1848
Index......Page 1893
