Magnetic Source Imaging of the Human Brain

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This book is designed to acquaint serious students, scientists, and clinicians with magnetic source imaging (MSI)--a brain imaging technique of proven importance that promises even more important advances. The technique permits spatial resolution of neural events on a scale measured in millimeters and temporal resolution measured in milliseconds. Although widely mentioned in literature dealing with cognitive neuroscience and functional brain imaging, there is no single book describing both the foundations and actual methods of magnetoencephalopgraphy and its underlying science, neuromagnetism. This volume fills a long-standing need, as it is accessible to scientists and students having no special background in the field, and makes it possible for them to understand this literature and undertake their own research. A self-contained unit, this book covers MSI from beginning to end, including its relationship to allied technologies, such as electroencephalography and modern functional imaging modalities. In addition, the book: *introduces the field to the non-specialist, providing a framework for the rest of the book; *provides a thorough review of the physiological basis of MSI; *describes the mathematical bases of MSI--the forward and inverse problems; *outlines new signal processing methods that extract information from single-trial MEG; *depicts the early, as well as the most recent versions of MSI technology; *compares MSI with other imaging methodologies; *describes new paradigms and analysis techniques in applying MSI to study human perception and cognition, which are also applicable to EEG; and *reviews some of the most important results in MSI from the most prominent researchers and laboratories around the world.

Author(s): Zhong-Lin Lu, Lloyd Kaufman
Edition: 1
Publisher: Routledge
Year: 2003

Language: English
Pages: 421
Tags: Медицинские дисциплины;Неврология и нейрохирургия;

Contents......Page 6
Preface......Page 10
1 Basics of Neuromagnetism and Magnetic Source Imaging......Page 14
2 Toward Understanding the Physiological Origins of Neuromagnetic Signals......Page 56
3 Forward Problem Solution of Magnetic Source Imaging......Page 90
4 Magnetic Source Imaging: Search for Inverse Solutions......Page 114
5 Techniques for Investigating and Exploiting Nonlinearities in Brain Processes by Recording Responses Evoked by Sensory Stimuli......Page 148
6 Independent Components of Magnetoencephalography: Localization and Single-Trial Response Onset Detection......Page 172
7 Toward Noise-Immune Magnetoencephalography Instrumentation......Page 218
8 Full-Sensitivity Biomagnetometers: Sam Williamson's Vision Brought to Life......Page 232
9 From 1- to 306-Channel Magnetoencephalography in 15 Years: Highlights of Neuromagnetic Brain Research in Finland......Page 246
10 Magnetoencephalography: From Pioneering Studies to Functional Brain Imaging......Page 258
11 Optical Imaging of Brain Function and the Relation Between Neuronal Activity and Hemodynamics in Health and Disease......Page 274
12 High-Frequency Oscillations From the Human Somatosensory Cortex: The Interneuron Hypothesis......Page 296
13 Measuring Sensory Memory: Magnetoencephalography Habituation and Psychophysics......Page 334
14 Clinical Applications of Brain Magnetic Source Imaging......Page 358
Epilogue......Page 380
B......Page 392
C......Page 393
D......Page 394
F......Page 395
H......Page 396
K......Page 398
L......Page 399
M......Page 400
N......Page 401
P......Page 402
S......Page 403
T......Page 405
W......Page 406
Z......Page 407
A......Page 408
C......Page 409
E......Page 410
F......Page 411
H......Page 412
L......Page 413
M......Page 414
N......Page 416
R......Page 417
S......Page 418
Z......Page 421