Cell separation is at the core of current methods in experimental biology and medicine. Its importance is illustrated by the large number of physical and biochemical principles that have been evaluated for application to cell separation. The development of cell separation methods is driven by the needs of biological and medical research, and the ever increasing demands for sensitivity, selectivity, yield, timeliness and economy of the process. The interdisciplinary nature of research in this area and the volume of information available in research publications and conferences necessitates a a basic description of the fundamental processes involved in magnetic cell separation that may help the user in navigating this wealth of information available online and in scientific publications. This book will appeal to researchers in many areas utilizing this technique including those working in cell biology, clinical research, inorganic chemistry, biochemistry, chemical engineering, materials science, physics and electrical engineering. * Provides examples of how to calculate the volume magnetic susceptibility, a fundamental quantity for calculating the magnetic force acting on a cell, from various types of magnetic susceptibilities available in literature * Introduces the elements of magnetostatics as they apply to cell magnetization and the magnetization of magnetic micro- and nano- particles used for cell separation * Describes the parameters used to determine cell magnetophoresis
Author(s): M. Zborowski and J. J. Chalmers (Eds.)
Series: Laboratory techniques in biochemistry and molecular biology 32
Edition: 1st ed
Publisher: Elsevier
Year: 2008
Language: English
Pages: 1-454
City: Amsterdam; Boston
Content:
Magnetic susceptibility Review Article
Pages 1-28
Maciej Zborowski
Magnetic formulary Review Article
Pages 29-61
Maciej Zborowski
Maxwell stress and magnetic force Review Article
Pages 63-79
Maciej Zborowski
Basic magnetic field configurations Review Article
Pages 81-104
Maciej Zborowski
Magnetophoresis Review Article
Pages 105-118
Maciej Zborowski
Synthesis and characterization of nano‐ and micron‐sized iron oxide and iron particles for biomedical applications Review Article
Pages 119-162
Shlomo Margel, Tammy Lublin‐Tennenbaum, Sigalit Gura, Merav Tsubery, Udi Akiva, Nava Shpaisman, Anna Galperin, Benny Perlstein, Polina Lapido, Yonit Boguslavsky, Jenny Goldshtein, Ofra Ziv
The biocompatibility and toxicity of magnetic particles Review Article
Pages 163-223
Urs O. Häfeli, Jennifer Aue, Jaime Damani
Analytical magnetic techniques in biology Review Article
Pages 225-247
Jeffrey J. Chalmers, Lee R. Moore
Preparative applications of magnetic separation in biology and medicine Review Article
Pages 249-264
Jeffrey J. Chalmers, Xiaodong Tong, Oscar Lara, Lee R. Moore
Commercial magnetic cell separation instruments and reagents Review Article
Pages 265-292
Maciej Zborowski
Worked examples of cell sample preparation and magnetic separation procedures Review Article
Pages 293-330
Maciej Zborowski, Lee R. Moore, Kristie Melnik, Ying Jing
New challenges and opportunities Review Article
Pages 331-412
Maciej Zborowski, P. Stephen Williams, Lee R. Moore, Jeffrey J. Chalmers, Peter A. Zimmerman
Nomenclature, abbreviations, units, and conversion factors Review Article
Pages 413-420
Maciej Zborowski, Jeffrey J. Chalmers
Vector notation Review Article
Pages 421-426
Maciej Zborowski, Jeffrey J. Chalmers
Magnetic body force and the Maxwell stresses Review Article
Pages 427-442
Maciej Zborowski, Jeffrey J. Chalmers
Volume magnetic susceptibilities of selected substances Review Article
Pages 443-444
Maciej Zborowski, Jeffrey J. Chalmers
Preface
Pages XI-XVIII
Maciej Zborowski, Jeffrey J. Chalmers
Subject Index
Pages 445-454
Table of Contents
Pages V-X
Series Editors
Page II
