Long-Range Control of Gene Expression

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This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. * Includes information on aspergillus genomes * Discusses sex and its role in virulence of human fungal pathogens * Covers the genomic analysis of neurospora

Author(s): Veronica van Heyningen and Robert E. Hill (Eds.)
Series: Advances in Genetics 61
Edition: 1
Publisher: Academic Press
Year: 2008

Language: English
Pages: 1-399

Content:
Contributors to Volume 61
Pages XI-XII

Preface
Pages XIII-XV
Robert E. Hill, Veronica van Heyningen

Chapter 1 Chromatin Structure and the Regulation of Gene Expression: The Lessons of PEV in Drosophila Review Article
Pages 1-43
Jack R. Girton, Kristen M. Johansen

Chapter 2 Polycomb Group Proteins and Long‐Range Gene Regulation Review Article
Pages 45-66
Julio Mateos‐Langerak, Giacomo Cavalli

Chapter 3 Evolution of Cis‐Regulatory Sequences in Drosophila Review Article
Pages 67-106
Pat Simpson, Savita Ayyar

Chapter 4 β‐Globin Regulation and Long‐Range Interactions Review Article
Pages 107-142
Robert‐Jan Palstra, Wouter de Laat, Frank Grosveld

Chapter 5 Long‐Range Regulation of α‐Globin Gene Expression Review Article
Pages 143-173
Douglas R. Higgs, Douglas Vernimmen, Bill Wood

Chapter 6 Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution Review Article
Pages 175-205
Francois Spitz, Denis Duboule

Chapter 7 Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators Review Article
Pages 207-223
Le‐Ben Wan, Marisa S. Bartolomei

Chapter 8 Genomic Imprinting and Imprinting Defects in Humans Review Article
Pages 225-246
Bernhard Horsthemke, Karin Buiting

Chapter 9 Epigenetic Gene Regulation in Cancer Review Article
Pages 247-267
Esteban Ballestar, Manel Esteller

Chapter 10 Genomic Identification of Regulatory Elements by Evolutionary Sequence Comparison and Functional Analysis Review Article
Pages 269-293
Gabriela G. Loots

Chapter 11 Regulatory Variation and Evolution: Implications for Disease Review Article
Pages 295-306
Emmanouil T. Dermitzakis

Chapter 12 Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes Review Article
Pages 307-338
Adam Woolfe, Greg Elgar

Chapter 13 Long‐Range Gene Control and Genetic Disease Review Article
Pages 339-388
Dirk A. Kleinjan, Laura A. Lettice

Index
Pages 389-399