Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications presents an overview of the most recent applications of lipospheres primarily in the field of medicine, pharmaceutics and biotechnology. Included are chapters on preparation, characterization, delivery (of peptides, proteins, vaccines, nucleic acids) therapeutic applications to different systems and suggestions for further research. Including numerous illustrations, tables and photos, this book provides procedures for specific applications and biological systems and shows lipospheres as a technical solution to various problems associated with controlled release of biochemicals.
Author(s): Claudio Nastruzzi
Edition: 1
Publisher: CRC Press
Year: 2004
Language: English
Pages: 22
CONTENTS......Page 0
CONTENTS......Page 1
1.2 INTRODUCTION TO COLLOIDAL DRUG CARRIERS......Page 2
1.3 FROM NANOEMULSIONS TO NANOPELLETS: SLN — HISTORY AND SCOPE......Page 3
1.4.2.1 High-Shear Homogenization and Ultrasound......Page 4
1.4.2.2.1 Hot Homogenization......Page 5
1.4.2.3 SLN Prepared by Solvent Emulsification/Evaporation......Page 6
1.4.2.6 Comparison of Different Formulation Procedures......Page 7
1.4.2.7.1 Influence of the Lipid......Page 9
1.4.2.7.2 Influence of the Emulsifier......Page 10
1.4.3 STERILIZATION......Page 11
1.4.4 STABILIZATION BY DRYING......Page 12
1.5 CHARACTERIZATION OF SLN......Page 14
1.6 ADVANTAGES AND DISADVANTAGES OF SLN AND NLC......Page 17
REFERENCES......Page 18
