Lehninger Principles of Biochemistry

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"Clear writing and illustrations…Clear explanations of difficult concepts…Clear communication of the ways in biochemistry is currently understood and practiced. For over 35 years, in edition after bestselling edition, Principles of Biochemistry has put those defining principles into practice, guiding students through a coherent introduction to the essentials of biochemistry without overwhelming them. The new edition brings this remarkable text into a new era. Like its predecessors, Lehninger Principles of Biochemistry, Sixth Edition strikes a careful balance of current science and enduring concepts, incorporating a tremendous amount of new findings, but only those that help illustrate biochemistry’s foundational principles. With this edition, students will encounter new information emerging from high throughput DNA sequencing, x-ray crystallography, and the manipulation of genes and gene expression, and other techniques. In addition, students will see how contemporary biochemistry has shifted away from exploring metabolic pathways in isolation to focusing on interactions among pathways. They will also get an updated understanding of the relevance of biochemistry to the study of human disease (especially diabetes) as well as the important role of evolutionary theory in biochemical research. These extensive content changes, as well as new art and powerful new learning technologies make this edition of Lehninger Principles of Biochemistry the most impressive yet."

Author(s): Albert Lehninger; David L. Nelson; Michael M. Cox
Edition: 6th
Publisher: W. H. Freeman
Year: 2012

Language: English
Commentary: Thanks to torrents
Pages: 1336
Tags: Биологические дисциплины;Биохимия;

Preface vi

1 The Foundations of Biochemistry 1

I STRUCTURE AND CATALYSIS 45

2 Water 47
3 Amino Acids, Peptides, and Proteins 75
4 The Three-Dimensional Structure of Proteins 115
5 Protein Function 157
6 Enzymes 189
7 Carbohydrates and Glycobiology 243
8 Nucleotides and Nucleic Acids 281
9 DNA-Based Information Technologies 313
10 Lipids 357
11 Biological Membranes and Transport 385
12 Biosignaling 433

II BIOENERGETICS AND METABOLISM 501

13 Bioenergetics and Biochemical Reaction Types 505
14 Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway 543
15 Principles of Metabolic Regulation 587
16 The Citric Acid Cycle 633
17 Fatty Acid Catabolism 667
18 Amino Acid Oxidation and the Production of Urea 695
19 Oxidative Phosphorylation and Photophosphorylation 731
20 Carbohydrate Biosynthesis in Plants and Bacteria 799
21 Lipid Biosynthesis 833
22 Biosynthesis of Amino Acids, Nucleotides, and Related Molecules 881
23 Hormonal Regulation and Integration of Mammalian Metabolism 929

III INFORMATION PATHWAYS 977

24 Genes and Chromosomes 979
25 DNA Metabolism 1009
26 RNA Metabolism 1057
27 Protein Metabolism 1103
28 Regulation of Gene Expression 1155
Abbreviated Solutions to Problems AS-1
Glossary G-1
Credits C-1
Index I-1