Advancement in the field of nanotechnology has revolutionized the field of medicines and pharmaceuticals in the twentieth century. The proper use of nanomaterials in medical applications requires a proper understanding of these compounds. This correct understanding, beyond the physical and chemical properties, must also have the correct logic of use. In other words, the strategic use of nanomaterials with applicable perspective can also help to advance research, but if we go forward with the current research perspective that leads to the expansion of inapplicable researches, the intrinsic importance of using these nanomaterials is eliminated.
This book, considering the importance of nanomaterials and their application in medicine, as well as the significant growth of biomaterials in research fields, introduces the variables law (Rabiee's theory) for the implementation of this research and the establishment of a proper strategy. Considering that the degree of number of biomaterial and host variables follow a variety factors, and by increasing the degree of number of biomaterials and host variables, the degree of total variables also increases and as a result, performance and, consequently, biomaterial behavior in the host environment will have less control and predictive capabilities. For an external substance that is supposed to be in the human body, it must be predictable and controllable, In addition, according to the principle that the host in a fixed person does not have the ability to change, therefore, by using the simpler biomaterials (with less variables), the above goal is more accessible. It should be noted that in addition to observing biocompatibility tests for a biomaterial based on existing protocols and standards, the Applicable Compatibility (AC) parameter is also required in accordance with Rabiee's theory. This book is written in accordance with Rabiee's theory and the contents of this book should be evaluated from this perspective.
Author(s): Mohammad Rabiee, Navid Rabiee, Reza Salarian
Series: IOP Concise Physics
Publisher: IOP Publishing
Year: 2019
Language: English
Pages: 112
City: Bristol
PRELIMS.pdf
Preface
Acknowledgements
Author biographies
Mohammad Rabiee
Navid Rabiee
Reza Salarian
Ghazal Rabiee
CH001.pdf
Chapter 1 Nanomaterials: concepts
1.1 Nanomaterials
1.2 Metallic nanoparticles
1.3 Liposomes
1.4 Dendrimers
1.5 Nanomaterials classifications
1.6 Fabrication methods
References
CH002.pdf
Chapter 2 Bioactive nanomaterials
2.1 Polymers as bioactive materials
2.1.1 Non-biodegradable polymers
2.1.2 Biodegradable polymers
2.2 Composites as bioactive materials
2.3 Biodegradable metals as bioactive materials
2.4 Glass/ceramics as bioactive materials
2.5 Mechanical behavior of bioactive glasses
References
CH003.pdf
Chapter 3 Bio-inspired approaches: carbon-based nanomaterials
3.1 Carbon-based nanomaterials as a therapeutic platform
3.2 Cargo attachment
3.3 Cell targeting
3.4 Cargo delivery
3.5 Non-targeted cargo delivery
3.6 Bioimaging
3.7 Future biomedical challenges
References
CH004.pdf
Chapter 4 Nanomaterials and biomedical applications
4.1 Nanomaterials and tissue engineering
4.2 Remodeling induced by myocardial infarction
4.3 Remodeling induced by hypertension
4.4 Recent pharma approaches
References
CH005.pdf
Chapter 5 Enzyme-responsive nanomaterials
5.1 Introduction
5.2 Hydrolase-responsive nanomaterials
5.2.1 Protease-responsive nanomaterials
5.2.2 Trypsin-responsive nanomaterials
5.2.3 Elastase-responsive nanomaterials
5.2.4 Lipase-responsive nanomaterials
5.2.5 Glycosidase-responsive nanostructures
5.2.6 Other hydrolase-responsive nanomaterials
5.3 Oxidoreductase-responsive drug delivery systems
5.3.1 Glucose oxidase
5.3.2 Peroxidase
5.3.3 Azoreductase
5.3.4 Glutathione reductase
References
CH006.pdf
Chapter 6 Porphyrin-based nanomaterials
6.1 Introduction
6.2 Porphyrin-based nanomaterials: drug delivery systems
6.3 A novel approach: application of porphyrin-based covalent triazine metal–organic frameworks in drug delivery systems
6.4 A novel strategy: selective surface drug delivery systems
6.5 Nanomedicine applications
6.5.1 Cancer theranostics
6.5.2 X-ray induced photodynamic therapy (PDTX)
6.5.3 Liposomal porphyrins for cancer theranostics
6.5.4 Cerasomal porphyrin for the photodynamic theranostics of cancer
6.5.5 Porphysomes for cancer theranostics
6.6 A novel delivery system: porphyrin-based nanoparticles
6.6.1 Membrane-coated nanocarriers: targeted delivery system
6.6.2 Virus-like particles (VLPs)
6.6.3 Extracellular vesicles
6.7 Future perspective applications
6.7.1 Cardiac repairing
6.7.2 Ocular drug delivery
6.8 Conclusion
References
