The second edition of Introduction to Microfluidics captures all the new exciting developments in the field of microfluidics over the last twenty years. While maintaining the same clear structure, and accessible explanations of the basic theory, this new edition is a complete revision of the first edition and makes use of the considerable data collected in the field over the last two decades.
The book describes the applications, the market, and attempts to envision the future of microfluidics. It covers the physics of miniaturization, the hydrodynamics of microfluidics in channels and with droplets, transport phenomena in microsystems, electrokinetic phenomena, and an introduction to microfabrication. The basic principles are explored in depth and with rigor, and their main applications are clearly presented. Many examples are provided and discussed simply, most often from a physical perspective, and the book includes 415 figures and 600 references.
Offering a cross-disciplinary view of the field embracing biological, chemical, physical and engineering perspectives, this book is an ideal resource for students and researchers at any level.
Author(s): Patrick Tabeling
Edition: 2
Publisher: Oxford University Press
Year: 2023
Language: English
Pages: 478
City: Oxford
Cover
Titlepage
Copyright
Dedication
Preface
Acknowledgements
Contents
1 Introduction
1.1 Astonishing microfluidic systems in nature
1.2 Exquisite microfluidic control in the human body
1.3 MEMS, the mother of microfluidics
1.4 The birth of microfluidics
1.5 The advent of soft technology
1.6 Diversification of the technology and broadening of the applications
1.7 MicroReaction Technology (MRT)
1.8 Nanofluidics
1.9 The microfluidic market
1.10 Future of microfluidics
1.11 Reviews and books
1.12 Organization of the book
References
2 Physics at the microscale
2.1 The scales of small things
2.2 Intermolecular Forces - basics
2.3 Nano-Micro and Millifluidics
2.4 The physics of miniaturization
2.5 Scaling laws in nature
2.6 Miniaturization of electrostatic systems
2.7 Miniaturization of electromagnetic systems
2.8Miniaturization of mechanical systems - the vibrating microbeam
2.9 Miniaturization of thermal systems
2.10 Sampling and throughput
References
3 Hydrodynamics of microfluidics 1: channels
3.1 The flow equations and the boundary conditions
3.2 Slippage in gases
3.3 Slippage in liquids
3.4 Microfluidics at small Reynolds numbers
3.5 Resistances and capacitances in microfluidics
3.6 Inertial microfluidics and millifluidics
References
4 Hydrodynamics of microfluidics 2: droplets
4.1Liquid–vapour interfaces
4.2 Laplace's law
4.3 Surfactants
4.3 Wetting
4.5 Droplets advancing on a surface
4.6 The governing equations and the capillary number
4.7 The Landau–Levich and Bretherton films
4.8 The Rayleigh–Plateau instability
4.9 Washburn law and paper microfluidics
4.10 Production of microfluidic droplets and bubbles
4.11 Characteristics of microfluidic droplets and bubbles
References
5 Transport in microfluidics
5.1 The microscopic origin of diffusion
5.2 Advection-diffusion equation and its properties
5.3 Analysis of diffusion phenomena
5.4 Analysis of dispersion phenomena
5.5 Brief introduction to chaos and chaotic mixing
5.6 Mixing in microfluidic devices
5.7 Four applications of transport of matter in microfluidics
5.8 Transport of matter across interfaces
5.9 Particles and microfluidics
5.10 Particles in inertial regimes
5.11 Adsorption
5.12 Chromatography
5.13 Thermal transport by conduction
5.14 Convection-diffusion heat equation and properties
5.15 Heat transfer in the presence of a flow in microsystems
5.16 Evaporation and drying
5.17 Microexchangers for electronic components
References
6 Electrokinetics
6.1 Introduction
6.2 Basic notions of electrostatics of macroscopic media
6.3 The electrokinetic equations
6.4 The electrical double layer
6.5 Electro-osmosis
6.6 Electrophoresis
6.7 Microfluidic electrokinetic separation
6.8 Dielectrophoresis
6.9 Three illustrations/applications of dielectrophoresis
6.10 Electrowetting
References
7 An introduction to microfabrication
7.1 Introduction
7.2 Current situation of microtechnologies
7.3 The environment of microfabrication
7.4 Photolithography
7.5 Direct writing or maskless photolithography
7.6 Microfabrication methods for silicon and glass devices
7.7 PDMS-based moulding – soft lithography
7.8 Computer Numerical Control (CNC) Micromilling
7.9 3D Printing or Additive Manufacturing (AM)
7.10 Paper microfluidics
7.11 Other technologies
References
Index
