Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist.
Author(s): Yasumasa Nishimura, Ritsuko Komaki (eds.)
Edition: 1
Publisher: Springer Tokyo
Year: 2015
Language: English
Pages: 473
Tags: Radiotherapy; Oncology; Medical and Radiation Physics
Front Matter....Pages i-viii
Front Matter....Pages 1-1
History of IMRT....Pages 3-14
Principles of IMRT....Pages 15-42
Radiobiology for IMRT....Pages 43-57
Treatment Planning of IMRT for Head and Neck Malignancies....Pages 59-84
IGRT for IMRT....Pages 85-112
Adaptive Radiation Therapy in Intensity-Modulated Radiation Therapy for Head and Neck Cancer....Pages 113-127
Front Matter....Pages 129-129
Brain Tumor: How Should We Manage Glioblastoma in the Era of IMRT?....Pages 131-151
Nasopharyngeal Cancer....Pages 153-169
Oropharyngeal Cancer....Pages 171-192
Postoperative Intensity-Modulated Radiation Therapy for Head and Neck Cancers: A Case-Based Review....Pages 193-213
Sequelae of Therapy of Head and Neck Cancer: Their Prevention and Therapy....Pages 215-248
Non-small Cell Lung Cancer....Pages 249-260
Mesothelioma....Pages 261-273
Breast Cancer....Pages 275-288
Clinical Application of IMRT for Cervical Esophageal Cancer....Pages 289-299
Thoracic Esophageal Cancer....Pages 301-314
Pancreatic CancerPancreatic Cancer ....Pages 315-336
Anal Canal Cancer....Pages 337-354
Early Prostate Cancer (T1–2N0M0)....Pages 355-377
Intensity-Modulated Radiation Therapy for Locally Advanced Prostate Cancer....Pages 379-402
Front Matter....Pages 129-129
Gynecologic Malignancies....Pages 403-441
Pediatric Cancers....Pages 443-465
Back Matter....Pages 467-473
