Influence of storage conditions on the stability of lactide

Glotova V.N., Zamanova M.K., Yarkova A.V., Krutas D.S., Izhenbina T.N., Novikov V.T. — Procedia Chemistry. — 2014. — V. 10. — P. 252-257. — DOI 10.1016/j.proche.2014.10.042.The objective following of the present study was to investigate the effect of different storage time and conditions on the stabilityof lactide. In this study the samples of lactide with different purities were stored under three various storage conditions and thecompound integration was monitored for a period of 2 weeks. The storage conditions selected were (1) in the desiccator, (2) inthe glove box under argon and (3) under ambient atmosphere. The purity of samples was performed on HPLC and Karl Fischertitration during all period of storage. It was shown that the initial purity of the lactide has a significant bearing on the lactide degradation.