Contains patterns of allergic reactivity for disorders such as asthma, atopic dermatitis, urticaria, and anaphylaxis. Written by leading experts in the field, Inflammatory Mechanisms in Allergic Diseases covers non-anaphylactic drug disorders; synthesis and formation of IgE antibodies; new treatments using allergenic peptides, immunostimulatory oligonucleotides, and pharmacogenomics;recent advances targeting effector mechanisms; hypersensitivity reactions to drugs and more! With over 3100 references, tables, drawings, and micrographs, Inflammatory Mechanisms in Allergic Diseases is an essential reference for allergists, pulmonologists, immunologists, dermatologists, ophthalmologists, otolaryngologists, internists, pediatricians, family practitioners, and medical students in these disciplines.
Author(s): Burton Zweiman, Lawrence B. Schwartz
Series: Clinical Allergy and Immunology, 16
Publisher: CRC Press
Year: 2021
Language: English
Pages: 599
City: Boca Raton
Cover
Half Title
Series Page
Title Page
Copyright Page
Series Introduction
Preface
Table of Contents
Contributors
Part One: Introduction
1: Introduction
Part Two: Components in the Allergic Inflammatory Response
2: Mast Cells and Basophils
3: Eosinophils
4: Neutrophils
5: Lymphocytes
6: Leukocyte–Blood Vessel Interactions
7: Extracellular Matrix
8: The Regulation of IgE Synthesis
9: Effector Roles of IgE Antibodies: Targeting Allergen to the High-Affinity IgE Receptor for Fc. RI-Dependent Signaling and Antigen Presentation
10: Lipid Inflammatory Mediators: Leukotrienes, Prostaglandins, Platelet-Activating Factor
11: Cytokines in Allergic Inflammation
Part Three: Allergic Inflammatory Mechanisms in Clinical Disorders
12: Mechanisms of Allergic Rhinitis
13: Nasal Polyps and Sinusitis
14: Allergic Eye Disorders
15: Asthma
16: Atopic Dermatitis
17: Urticaria
18: Anaphylaxis and Inflammation
19: Nonanaphylactic Drug Disorders
20: Vasculitis
21: Allergic Bronchopulmonary Aspergillosis, Allergic Fungal Sinusitis, and Hypersensitivity Pneumonitis
Part Four: Emerging Concepts in the Modulation of Allergic Inflammation
22: Pharmacological Approaches
23: Synthetic and Genetically Engineered Allergen Derivatives for Specific Immunotherapy of Type I Allergy
24: Anti-IgE Antibody Therapy
25: Allergen Injection Immunotherapy
26: DNA Immunomodulation of Asthma
Part Five: Overall Summary/Conclusions
27: Mechanisms of Allergic Disease and the Implications for Therapeutic Interventions
Index
About the Editors
