Immunopharmacology focuses on the mechanism of action of pharmacologic agents that regulate immune response and the physiologic, pathologic, and pharmacologic role of the products of immune response. Topics include cytokines and their receptors, immunosuppressive drugs, monoclonal antibodies, mechanisms and immunotherapy of allergic disease, clinical transplantation, acquired immune deficiency disease, regulatory T cells, and gene therapy. The book provides most basic principles of immunopharmacology by equally emphasizing the disciplines of immunology and pharmacology, which will be a very valuable tool for both the professional as well as graduate students.
Author(s): Manzoor M. Khan (auth.)
Edition: 1
Publisher: Springer US
Year: 2008
Language: English
Pages: 266
City: New York
Tags: Pharmacology/Toxicology; Immunology; Biochemistry, general; Human Physiology; Human Genetics
Front Matter....Pages i-xiv
Overview of the Immune Response....Pages 1-32
Role of Cytokines....Pages 33-59
Cytokine Receptors and Signaling....Pages 61-86
Immunosuppressive Agents....Pages 87-105
Monoclonal Antibodies as Therapeutic Agents....Pages 107-126
Allergic Disease....Pages 127-147
Tissue Transplantation....Pages 149-170
Acquired Immune Deficiency Syndrome....Pages 171-201
Regulatory T Cells and Disease State....Pages 203-226
Gene Therapy....Pages 227-252
Back Matter....Pages 253-266