Immunology: An Illustrated Outline is both a guide to the essential principles of immunology and a concise dictionary of immunological terms. The book can be used to consolidate understanding in preparation for course exams and medical licensing exams, or as a refresher when immunology is encountered in related life sciences, such as microbiology, virology, and zoology.
The book is organized into five sections that represent the major topics in basic and clinical immunology. The Sixth Edition has been comprehensively revised to highlight the latest understanding of the field, particularly in the areas of innate immune defenses and antibody-based therapeutics.
Concise explanations of immunological terms
Full-color illustrations and micrographs to reinforce the text
Each topic is set out in single- or double-page spreads
Tables collate and summarize detailed information
Author(s): David Male
Edition: 6
Publisher: CRC Press, Taylor & Francis
Year: 2021
Language: English
Tags: Immunology; Medical Microbiology; Virology; Infectious Diseases; Immunopathology; Autoimmune Diseases
Cover
Half Title
Title Page
Copyright Page
Preface
Contents
Index of Terms
Chapter 1: The Immune System
Introduction
Lymphocytes
Innate lymphoid cells
Markers
Antigen-presenting cells
Phagocytes and auxiliary cells
Lymphoid system
Leukocyte development
Thymus and T-cell development
Lymph nodes
Spleen
Gut-associated lymphoid tissue (GALT)
Chapter 2: Immune Recognition
Antigen receptors
Antibody structure
Antibody-structural variations
Antibody functions
Antibody genes
Antibody biotechnology
Immunotherapeutic agents
Antigen-antibody interaction
T-cell antigen receptor (TCR)
T-cell receptor genes
MHC molecules
MHC genes
Immune recognition by NK cells
Innate immune recognition
Chapter 3: Immune Responses
Adaptive and innate immunity
Antibody response
Cell cooperation
Antigen presentation
T-cell activation
B-cell activation
Cytokines and cytokine receptors
Phagocytosis
Complement receptors
Fc receptors
Phagocyte microbicidal systems
Intracellular receptors for pathogens
Cytotoxicity
Inflammation
Mechanisms of cell migration
Chemokines and chemokine receptors
Complement
Immunoregulation
Neuroendocrine regulation
Tolerance
Genetic polymorphism in the immune response
Immunosuppression
Immunopotentiation
Vaccines
Chapter 4: Immunopathology
Immunodeficiency
Transplantation
MHC disease associations
MHC typing
Autoimmune disease
Animal models and mutant strains
Hypersensitivity
Type I (immediate) hypersensitivity
Type II (antibody-mediated) hypersensitivity
Type III (immune-complex-mediated) hypersensitivity
Type IV (delayed) hypersensitivity (DTH)
Chapter 5: Immunological Techniques
Antibodies and antigens
Clones and cell lines
Isolation of cells
Cellular functions
