This textbook focuses on the nascent field of Immunoepidemiology that addresses how differences in immune responses among individuals affect the epidemiology of infectious diseases, cancer, hypersensitivity, and autoimmunity. The idea for the book originated from a course entitled “Immunology for Epidemiologists“ at the Yale School of Public Health. While many fine textbooks are available that address the immunological responses of individuals to pathogens, these provided very little information regarding how immunological variation among populations affects the epidemiology of disease. And yet, it has long been recognized that there is great immunologic diversity among people, which can have a profound effect on the epidemiology of disease. Careful review of the immunologic and epidemiologic literature revealed that there have been relatively few publications concerning immunoepidemiology and that no textbook is available on the subject. This textbook therefore aims to fill this void by providing a much-needed tool to comprehensively and efficiently teach immunoepidemiology. The book includes a section on the basic principles of immunology, and then applies them to particular examples of disease in human populations. The target audience for this text book are Masters of Public Health students. Others who should also find it of interest include PhD students in epidemiology, immunology, medical students, generalists, and specialists in immunology, infectious diseases, cancer, and rheumatology.
Author(s): Peter J. Krause (ed.), Paula B. Kavathas (ed.), Nancy H. Ruddle (ed.)
Publisher: Springer
Year: 2019
Language: English
Pages: 297
City: Cham
Front Matter ....Pages i-xxvii
Front Matter ....Pages 1-1
Introduction to Immunology, Epidemiology, and Immunoepidemiology (Linda M. Niccolai, Nancy H. Ruddle, Peter J. Krause)....Pages 3-17
Front Matter ....Pages 19-19
Organization and Cells of the Immune System (Paula B. Kavathas, Peter J. Krause, Nancy H. Ruddle)....Pages 21-38
Innate Immunity: Recognition and Effector Functions (Paula B. Kavathas, Peter J. Krause, Nancy H. Ruddle)....Pages 39-53
Adaptive Immunity: Antigen Recognition by T and B Lymphocytes (Paula B. Kavathas, Peter J. Krause, Nancy H. Ruddle)....Pages 55-74
Adaptive Immunity: Effector Functions, Regulation, and Vaccination (Paula B. Kavathas, Peter J. Krause, Nancy H. Ruddle)....Pages 75-95
Disorders of the Immune System (Paula B. Kavathas, Peter J. Krause, Nancy H. Ruddle)....Pages 97-107
Front Matter ....Pages 109-109
Immunoepidemiology of Selected Components of the Innate and Adaptive Immune Systems (Nancy H. Ruddle, Paula B. Kavathas)....Pages 111-125
Immunoepidemiology of Immune Dysfunction (Eric Meffre, Peter J. Krause, Nancy H. Ruddle)....Pages 127-148
Front Matter ....Pages 149-149
Immunoepidemiology of Mycobacterium tuberculosis (Camila D. Odio, Richard J. Bucala)....Pages 151-163
Immunoepidemiology of Human Immunodeficiency (Elijah Paintsil)....Pages 165-178
Fungal Immunoepidemiology (Marwan M. Azar)....Pages 179-191
Immunoepidemiology of Plasmodium falciparum malaria (Amy K. Bei, Sunil Parikh)....Pages 193-213
Immunoepidemiology of Cancer (Xiaomei Ma, Rong Wang)....Pages 215-224
Front Matter ....Pages 225-225
Modeling Approaches Toward Understanding Infectious Disease Transmission (Laura A. Skrip, Jeffrey P. Townsend)....Pages 227-243
Vaccines (Diane McMahon-Pratt)....Pages 245-264
Immunotherapy for Infectious Diseases, Cancer, and Autoimmunity (Peter J. Krause, Paula B. Kavathas, Nancy H. Ruddle)....Pages 265-276
Back Matter ....Pages 277-297
