Immune Cells, Inflammation, and Cardiovascular Diseases

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Inflammation, once considered a physiological response to foreign pathogens, is now recognized as a crucial pathological player in the initiation and progression of several chronic diseases, including diabetes, obesity, cancer, Alzheimer’s disease, Parkinson’s disease, and many others. Considering that cardiovascular diseases are a leading cause of death in the United States and worldwide, the identification of critical inflammatory processes is of utmost importance to devising new immune-based therapeutics that can be added to existing regimens. This book provides detailed information on aspects of inflammation and the manner in which immune activation pathways affect the progression of cardiovascular diseases and the repair/regeneration mechanisms of underlying diseased tissues.

Key Features

    • Outlines the role that inflammation plays in cardiovascular diseases

    • Describes a paradox – neutralization of cytokines that contribute to cardiovascular disease does not show benefit

    • Summarizes research on a variety of processes and mechanisms contributing to cardiovascular pathology

    • Contributions from an international team of leading cardiologists and cardiovascular immunologists

    Related Titles

    Roy, S., et al., eds. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions (ISBN 978-1-138-19955-2)

    Kong, A-N. T., ed. Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention (ISBN 978-1-138-19984-2)

    Dick, A., et al. Practical Manual of Intraocular Inflammation (ISBN 978-0-367-38720-4)

    Author(s): Shyam S. Bansal
    Series: Methods in Signal Transduction Series
    Publisher: CRC Press
    Year: 2022

    Language: English
    Pages: 264
    City: Boca Raton

    Cover
    Half Title
    Series
    Title
    Copyright
    Contents
    Editor Biography
    List of Contributors
    Introduction
    Chapter 1 Innate Immune System in Cardiovascular Diseases
    Chapter 2 Helper T-Lymphocytes in Cardiovascular Diseases
    Chapter 3 Glucocorticoid Signaling in the Heart
    Chapter 4 Transforming Growth Factor-β/Smad Signaling in Myocardial Disease
    Chapter 5 Fibroblast and Immune Cell Cross Talk in Cardiac Repair
    Chapter 6 Inflammation, Stem Cell Therapy, and Cardiac Repair
    Chapter 7 Cardiovascular Complications of Immune Checkpoint Inhibitors
    Chapter 8 Neuronal Regulation of the Immune System in Cardiovascular Diseases
    Chapter 9 Immune Responses Regulated by Exosomal Mechanisms in Cardiovascular Disease
    Chapter 10 Ion Channels in Immune Cells: Physiological and Pathophysiological Roles
    Index