This timely volume addresses the intimate pathophysiologic relationship between hypertension and cardiovascular disease. Hypertension is one of the most important global public health challenges, and its relationship to stroke and other catastrophic cerebrovascular diseases is an area of growing understanding. In this outstanding book, the editors and authors clearly and concisely synthesize our developing knowledge and place epidemiologic and physiologic information into a practical clinical context. Comprehensive chapters present the evidence supporting strategies for stroke prevention and care, including blood pressure lowering therapies, anti-coagulation, and management of other cerebrovascular risk factors. In addition to prescriptive measures for first stroke prevention, the book illuminates current regimens for care immediately after acute stroke and for the prevention of recurrent stroke. A unique section is dedicated to the exploration of the interaction between elevated blood pressure and brain function and cognition. The concluding chapter provides a resource towards optimizing the organization of stroke care. Hypertension and Stroke is of great utility for specialists in neurology and cardiovascular medicine and a valuable practical resource for all physicians caring for older adults and hypertensive patients.
Author(s): Raymond R. Townsend MD, Susan P. Steigerwalt MD, FASH, FACP (auth.), Venkatesh Aiyagari, Philip B. Gorelick (eds.)
Series: Clinical Hypertension and Vascular Diseases
Edition: 1
Publisher: Humana Press
Year: 2011
Language: English
Pages: 279
Tags: Neurology; Internal Medicine; Cardiology; General Practice / Family Medicine; Nephrology; Endocrinology
Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Blood Pressure: Definition, Diagnosis, and Management....Pages 3-19
The Link Between Hypertension and Stroke: Summary of Observational Epidemiological Studies....Pages 21-39
Blood Pressure Control and Primary Prevention of Stroke: Summary of Clinical Trial Data....Pages 41-59
Front Matter....Pages 61-61
Mechanisms Underlying Essential Hypertension: Neurogenic and Nonneurogenic Contributors....Pages 63-76
Pathophysiology and Mechanisms Whereby Hypertension May Cause Stroke....Pages 77-94
Front Matter....Pages 95-95
Cardiovascular Risk Assessment and Summary of Guidelines for the Management of Hypertension....Pages 97-113
Acute Blood Pressure Management After Ischemic Stroke....Pages 115-126
Hypertensive Encephalopathy and Acute Blood Pressure Management After Hemorrhagic Stroke....Pages 127-141
Recurrent Stroke Prevention I: Diuretic and Angiotensin-Converting Enzyme Inhibitors (ACEIs) – The PROGRESS Trial....Pages 143-157
Recurrent Stroke Prevention II: Angiotensin Receptor Blockers—The LIFE, MOSES, PRoFESS, and Other Trials....Pages 159-171
A Practical Guide to Recurrent Stroke Prevention....Pages 173-192
Front Matter....Pages 193-193
Vascular Cognitive Impairment and Alzheimer Disease: Are These Disorders Linked to Hypertension and Other Cardiovascular Risk Factors?....Pages 195-210
Cerebral Small Vessel Disease, Hypertension, and Cognitive Function....Pages 211-224
Cerebral Microbleeds, Small-Vessel Disease of the Brain, Hypertension, and Cognition....Pages 225-235
Imaging Effects of Hypertension on the Brain: A Focus on New Imaging Modalities and Options....Pages 237-255
Front Matter....Pages 257-257
The Joint Commission’s Initiatives to Improve Stroke Care and What It Means for Acute Stroke Care and Prevention....Pages 259-268
Back Matter....Pages 269-279
