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Human Retroviral Infections: Immunological and Therapeutic Control

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This book brings together experts in the field of human retroviral pathogenesis, vaccine development, and the clinical treatment of AIDS. The problems facing the development of an effective vaccine against HIV-1 is the ability of the virus, particularly in the immunogenic envelope glycoprotein, to undergo amino acid hypervariability, thus making a vaccine against one envelope glycoprotein ineffective against other viruses due to their mutability.

Author(s): Kenneth E. Ugen, Mauro Bendinelli, Herman Friedman
Edition: 1
Year: 2000

Language: English
Pages: 368