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Human gene evolution

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Author(s): David N Cooper, Dr
Publisher: Bios
Year: 1999

Language: English
Pages: 509
Tags: Биологические дисциплины;Генетика;Генетика человека;

Contents......Page 6
Preface......Page 12
Acknowledgements......Page 15
Abbreviations......Page 16
Websites cited in the text......Page 17
PART 1 INTRODUCTION AND OVERVIEW......Page 20
Structure and function in the human genome......Page 22
Evolution of the human genome......Page 74
PART 2 EVOLUTION OF GENE STRUCTURE......Page 124
Introns, exons, and evolution......Page 126
Genes and gene families......Page 158
Promoters and transcription factors......Page 240
Pseudogenes and their formation......Page 284
PART 3 MUTATIONAL MECHANISMS IN EVOLUTION......Page 314
Single base-pair substitutions......Page 316
Contractions and expansions in gene size and number......Page 348
Gross gene rearrangements......Page 408
Molecular reconstruction of ancient genes/ proteins......Page 442
Index to Human Gene Symbols used in text......Page 458
Index......Page 494