How New Humans Are Made: Cells and Embryos, Twins and Chimeras, Left and Right, Mind Self Soul, Sex, and Schizophrenia

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It is not okay to call something a miracle without even trying to understand it. This is human developmental biology (human embryology, in terms of cells and molecules) for everyone curious enough to see it through, from the perspective of the business of becoming human as individuals and as species; making new humans; how it happens (cells do it, ALL of it); and common variations of the process. It cannot be made quite simple and be kept quite true, but we will move as far toward simple as we can without losing touch with sound evidence. Variations from the normal version of the process, particularly malformations and twinning and chimerism, figure prominently in the story because there is no better way to learn about the usual than to study the unusual and see what differences in the endings these observable differences at the beginnings can make. In this book, when technical terminology is the only way, or the best way, to say what needs to be said, it is defined and explained making the words a worthwhile part of what is here to be learned. This book defines its own new field. We cannot claim to understand how anything [human] works [as human], with no effort at understanding the emergence of its form and functions. Old and new unanswered questions are waiting to be dug out from under old unquestioned answers about how becoming human unfolds. We will also address some popular and weighty, but deeply empty assertions about the circumstances and mechanisms of our beginnings and our ceaseless becoming. We will find fundamental questions from the humanities unanswerable except from biology. Human developmental biology is a foundational discipline within the humanities.

Author(s): Charles E. Boklage
Edition: 1
Year: 2010

Language: English
Pages: 516

Cover Page
......Page 1
Title Page
......Page 2
Copyright
......Page 5
Foreword
......Page 8
Acknowledgments......Page 10
Contents......Page 14
Introduction......Page 17

Orientation......Page 28
Human by [Cellular & Developmental]
Defi nition:
Emergence: of Mind, of Self, of Soul, of Person......Page 53
Genetic Twin Studies of Schizophrenia
Mind /Brain Asymmetry, Multifactorial Inheritance
and Epigenetic Variation......Page 80
Reviewing/Reciting The Orthodoxy......Page 110
On The Zygosity of Twins......Page 121
Most twins
(products of twin embryogenesis )
are not twins
(born as members of double pregnancies)......Page 135
Natural History and Epidemiology
of Twins and Twinning......Page 145
the Chorion, the Amnion and
the Vertebrate Body Plan......Page 184
Each of Us Was Once a Single Cell …
or Two
Meiosis, Gametogenesis,
Syngamy, Embryogenesis …......Page 207
Getting to the Bottom of
Creation’s Best Trick:
How Human Lives Begin......Page 249
Timing Is Everything......Page 268
Twins and Handedness and
[Illusions of ] Mirror-Imaging......Page 277
Twins and Malformations......Page 294
Twins and Teeth and (the Realities of )
Mirror-Imaging......Page 305
The Oddest of Couples: Boy-Girl Twins......Page 322
The Weinberg Tautology and
The Lingering Perfume of Red Herring......Page 334
Twinning and Spontaneous Chimerism......Page 357
Finding the Right Answer is Much Easier
After Finding the Right Question......Page 384
Normal Embryogenesis of
Left and Right, and Twins
and Chimeras......Page 405
The Logic of DNA Genotyping and
Forensic Implications of Chimerism......Page 423
Summary......Page 431
Bibliography......Page 437
Glossary......Page 446
Index......Page 501