HIV-1: Molecular Biology and Pathogenesis

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Author(s): Kuah-Teh Jeang (Eds.)
Series: Advances in Pharmacology 49
Edition: 2nd Edition
Publisher: Elsevier
Year: 2000

Language: English
Pages: 1-538

Content:
Editorial Board
Page ii

Contributors
Pages xv-xvii

Preface
Pages xix-xxi
Kuan-Teh Jeang

HIV therapeutics: Past, present, and future Original Research Article
Pages 1-40
Osama Abu-ata, Jihad Slim, Geirge Perez, Stephen M. Smith

HIV drug resistance and viral fitness Original Research Article
Pages 41-66
François Clavel, Esther Race, Fabrizio Mammano

Inhibitors of HIV- I reverse transcriptase Original Research Article
Pages 67-109
Michael A. Parniak, Nicolas Sluis-Cremer

HIV-I protease: Maturation, enzyme specificity, and drug resistance Original Research Article
Pages 111-146
John M. Louis, Irene T. Webert, József Tözsér, G. Marius Clore, Angela M. Gronenborn

HIV-I integrase inhibitors: Past, present, and future Original Research Article
Pages 147-156,IN1,157-165
Nouri Neamati, Christophe Marchand, Yves Pommier

Selection of HIV replication inhibitors: Chemistry and biology Original Research Article
Pages 167-197
Seongwoo Hwang, Natarajan Tamilarasu, Tariq M. Rana

Therapies directed against the rev axis of HIV autoregulation Original Research Article
Pages 199-228
Andrew I. Dayton, Ming Jie Zhang

HIV-I gene therapy: Promise for the future Original Research Article
Pages 229-261
Ralph Dornburg, Roger J. Pomerantz

Assessment of HIV vaccine development: Past, present, and future Original Research Article
Pages 263-314
Michael W. Cho

HIV-I-associated central nervous system dysfunction Original Research Article
Pages 315-385
Fred C. Krebs, Heather Ross, John McAllister, Brian Wigdahl

Molecular mechanisms of human immunodeficiency virus type I mother-infant transmission Original Research Article
Pages 387-416
Nafees Ahmad

Molecular epidemiology of HIV-I: An example of Asia Original Research Article
Pages 417-436
Mao-Yuan Chen, Chun-Nan Lee

Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and Prevention Original Research Article
Pages 437-477
Vanessa M. Hirsch, Jeffrey D. Lifson

Animal models for AIDS pathogenesis Original Research Article
Pages 479-514
John J. Trimble, Janelle R. Salkowitz, Harry W. Kestler

Index
Pages 515-526

Contents of previous volumes
Pages 527-538