Hepatocellular cancer is the the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today’s hepatologists and medical and surgical oncologists.
Author(s): Donna L. White PhD, MPH, Amir Firozi MD (auth.), Brian I. Carr (eds.)
Series: Current Clinical Oncology
Edition: 2
Publisher: Humana Press
Year: 2010
Language: English
Pages: 416
Tags: Oncology; Surgical Oncology; Hepatology; Interventional Radiology; Gastroenterology
Front Matter....Pages i-xv
Epidemiology of Hepatocellular Carcinoma....Pages 1-25
Environmental Carcinogens and Risk for Human Liver Cancer....Pages 27-53
Primary Liver Cancer: Chemical Carcinogenesis....Pages 55-107
Molecular Mechanisms of Hepatocellular Carcinoma: Insights to Therapy....Pages 109-130
Genomic Profiling of Human Hepatocellular Carcinoma....Pages 131-182
Pathologic Aspects of Hepatocellular Tumors....Pages 183-233
Hepatocellular Carcinoma Associated with Hepatitis B Virus....Pages 235-257
Hepatitis C and Hepatocellular Carcinoma....Pages 259-281
Metabolic Disease and Hepatocellular Carcinoma....Pages 283-307
Clinical Features and a Clinician’s Diagnostic Approach to Hepatocellular Carcinoma....Pages 309-326
Screening and Biomarkers for Hepatocellular Carcinoma....Pages 327-348
Use of Imaging Techniques to Screen for Hepatocellular Carcinoma....Pages 349-367
MRI for Detection and Evaluation of Hepatocellular Carcinoma....Pages 369-386
Ultrasound of Hepatocellular Carcinoma: The Important Contribution of Contrast Enhancement....Pages 387-406
Percutaneous Ethanol Injection....Pages 407-420
Radiofrequency Ablation of Hepatocellular Carcinoma....Pages 421-451
Resection of Hepatocellular Carcinoma....Pages 453-465
Liver Transplantation for Hepatocellular Carcinoma....Pages 467-490
Living Donor Liver Transplantation for Hepatocellular Carcinoma....Pages 491-525
Medical Therapy of HCC....Pages 527-568
Percutaneous Interventional Technique for Intra-arterial Chemoembolization....Pages 569-588
Molecular Targeted Therapies for HCC....Pages 589-614
Radiation Therapy for Hepatocellular Carcinoma....Pages 615-640
Psychosocial Issues in Hepatocellular Carcinoma....Pages 641-711
Putting It All Together....Pages 713-720
Back Matter....Pages 1-28
